Compile Data Set for Download or QSAR
maximum 50k data
Found 193 with Last Name = 'egashira' and Initial = 's'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295693(CHEMBL557629)
Affinity DataKi:  0.0340nMAssay Description:Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295693(CHEMBL557629)
Affinity DataKi:  0.0520nMAssay Description:Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295690((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity to human MCH1R expressed in CHO cells by scintillation counting per mg of proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295690((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...)
Affinity DataKi:  0.420nMAssay Description:Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295690((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295693(CHEMBL557629)
Affinity DataKi:  1.60nMAssay Description:Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295690((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...)
Affinity DataKi: >9.70E+3nMAssay Description:Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295692(CHEMBL555055 | tert-butyl 4-(1-(3,4-difluorophenyl...)
Affinity DataIC50:  0.240nMAssay Description:Displacement of[125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295692(CHEMBL555055 | tert-butyl 4-(1-(3,4-difluorophenyl...)
Affinity DataIC50:  0.240nMAssay Description:Displacement of[125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295690((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...)
Affinity DataIC50:  0.360nMAssay Description:Displacement of[125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295689(2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluoro-3H-s...)
Affinity DataIC50:  0.710nMAssay Description:Displacement of[125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295690((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...)
Affinity DataIC50:  0.710nMAssay Description:Displacement of[125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295690((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...)
Affinity DataIC50:  0.710nMAssay Description:Displacement of[125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295694(2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluoro-3H-s...)
Affinity DataIC50:  0.870nMAssay Description:Displacement of[125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295688(CHEMBL556697 | N-(3-(3H-spiro[isobenzofuran-1,4'-p...)
Affinity DataIC50:  1nMAssay Description:Displacement of[125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258449((+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine...)
Affinity DataIC50:  2.70nMAssay Description:Displacement of[125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295690((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human MCH1R expressed in CHO cells assessed as inhibition of MCH-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136699((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  25nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136711((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136714((S)-3,5-dichloro-N-(1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136718((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  35nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136720(CHEMBL343551 | N-[1-Benzyl-2-(6,7-dimethoxy-3,4-di...)
Affinity DataIC50:  36nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136694((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136693((+/-)-2-benzyl-1-(6,7-dimethoxy-3,4-dihydroisoquin...)
Affinity DataIC50:  56nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136701((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  59nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136703((+/-)-3-bromo-N-(1-(6,7-dimethoxy-3,4-dihydroisoqu...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136698((S)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136710((S)-N-(1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1...)
Affinity DataIC50:  195nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136719((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  240nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136702((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50:  395nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136705((+/-)-N-(1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2...)
Affinity DataIC50:  900nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136708((+/-)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydro...)
Affinity DataIC50:  910nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136699((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136695((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136717((+/-)-2-(4-bromobenzyl)-1-(6,7-dimethoxy-3,4-dihyd...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136704((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136714((S)-3,5-dichloro-N-(1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136707((R)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136697(2-Benzylamino-1-(6,7-dimethoxy-3,4-dihydro-1H-isoq...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136711((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136718((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50:  3.67E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136698((S)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50:  3.85E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136720(CHEMBL343551 | N-[1-Benzyl-2-(6,7-dimethoxy-3,4-di...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136693((+/-)-2-benzyl-1-(6,7-dimethoxy-3,4-dihydroisoquin...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136703((+/-)-3-bromo-N-(1-(6,7-dimethoxy-3,4-dihydroisoqu...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136717((+/-)-2-(4-bromobenzyl)-1-(6,7-dimethoxy-3,4-dihyd...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136697(2-Benzylamino-1-(6,7-dimethoxy-3,4-dihydro-1H-isoq...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136695((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136707((R)-2-(benzylamino)-1-(6,7-dimethoxy-3,4-dihydrois...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136702((+/-)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 193 total ) | Next | Last >>
Jump to: