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Found 21 with Last Name = 'elboray' and Initial = 'ee'
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50513317(CHEMBL4465620)
Affinity DataKi:  68nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50513318(CHEMBL4516553)
Affinity DataKi:  470nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50596052(CHEMBL5196484)
Affinity DataIC50:  87nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50595758(CHEMBL5207682)
Affinity DataIC50:  126nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50148781(CHEMBL3770903)
Affinity DataIC50:  300nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50513317(CHEMBL4465620)
Affinity DataIC50:  310nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50513320(CHEMBL4471909)
Affinity DataIC50:  370nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50595759(CHEMBL5175995)
Affinity DataIC50:  444nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50595760(CHEMBL5177373)
Affinity DataIC50:  457nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50596051(CHEMBL5183243)
Affinity DataIC50:  570nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50513318(CHEMBL4516553)
Affinity DataIC50:  600nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50596053(CHEMBL5173876)
Affinity DataIC50:  930nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50513319(CHEMBL4589851)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50595757(CHEMBL5174314)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50392111(CHEMBL2152613)
Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetRNA demethylase ALKBH5(Homo sapiens)
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50596051(CHEMBL5183243)
Affinity DataIC50:  7.13E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin) demethylation activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRNA demethylase ALKBH5(Homo sapiens)
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50596052(CHEMBL5196484)
Affinity DataIC50:  8.98E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin) demethylation activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)
Affinity DataIC50:  2.48E+4nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50513317(CHEMBL4465620)
Affinity DataIC50:  6.92E+4nMAssay Description:Inhibition of human N-terminal His-tagged SIRT3 (102 to 399 residues) expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50513317(CHEMBL4465620)
Affinity DataIC50:  7.74E+4nMAssay Description:Inhibition of human N-terminal His-tagged SIRT1 expressed in Escherichia coli using p53 (Arg-His-Lys-Lys(Ac)) (379 to 382 residues) as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50596052(CHEMBL5196484)
Affinity DataKd:  28nMAssay Description:Binding affinity to FTO (unknown origin) assessed as dissociation constant at 180 uM by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails PubMed