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Found 93 with Last Name = 'esposito' and Initial = 's'
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563230(CHEMBL4754949)
Affinity DataKi:  1.10nMAssay Description:Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563231(CHEMBL4780098)
Affinity DataKi:  2.88E+3nMAssay Description:Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50406432(CHEMBL5288562)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406430(CHEMBL5274747)
Affinity DataIC50:  4nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406429(CHEMBL5276842)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406431(CHEMBL5278011)
Affinity DataIC50:  6nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406376(CHEMBL5289332)
Affinity DataIC50:  47nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406428(CHEMBL5289545)
Affinity DataIC50:  64nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50:  71nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
LigandPNGBDBM50406374(CHEMBL5266583)
Affinity DataIC50:  74nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM392347(US10301278, Example 30)
Affinity DataIC50:  142nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50406427(CHEMBL5268861)
Affinity DataIC50:  290nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406386(CHEMBL5283114)
Affinity DataIC50:  409nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406425(CHEMBL5291140)
Affinity DataIC50:  435nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406390(CHEMBL5280924)
Affinity DataIC50:  436nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406393(CHEMBL5269591)
Affinity DataIC50:  521nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406424(CHEMBL5269651)
Affinity DataIC50:  664nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406400(CHEMBL5290199)
Affinity DataIC50:  797nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406377(CHEMBL5275116)
Affinity DataIC50:  808nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406366(CHEMBL5288762)
Affinity DataIC50:  887nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406430(CHEMBL5274747)
Affinity DataIC50:  900nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406426(CHEMBL5277049)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406385(CHEMBL5290866)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406429(CHEMBL5276842)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406432(CHEMBL5288562)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406431(CHEMBL5278011)
Affinity DataIC50:  4.20E+3nMAssay Description:In vitro inhibition of human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406379(CHEMBL5284334)
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406381(CHEMBL5268520)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50406368(CHEMBL5279504)
Affinity DataIC50: >6.40E+4nMAssay Description:Inhibition of dihydrofolate reductase in Candida albicans (in vitro).More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563189(CHEMBL4748830)
Affinity DataEC50:  45nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563190(CHEMBL4757578)
Affinity DataEC50:  143nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563191(CHEMBL4748931)
Affinity DataEC50:  20nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563192(CHEMBL4800116)
Affinity DataEC50:  146nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563193(CHEMBL4743958)
Affinity DataEC50:  393nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563194(CHEMBL4754697)
Affinity DataEC50:  522nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563195(CHEMBL4747756)
Affinity DataEC50:  124nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563196(CHEMBL4791290)
Affinity DataEC50:  32nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563197(CHEMBL4744303)
Affinity DataEC50:  498nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563198(CHEMBL4743539)
Affinity DataEC50:  17nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563199(CHEMBL4756139)
Affinity DataEC50:  46nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563200(CHEMBL4792874)
Affinity DataEC50:  202nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563201(CHEMBL4781482)
Affinity DataEC50:  929nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563202(CHEMBL4761424)
Affinity DataEC50:  200nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563203(CHEMBL4765167)
Affinity DataEC50:  897nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563204(CHEMBL4791486)
Affinity DataEC50:  54nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563205(CHEMBL4785899)
Affinity DataEC50:  92nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563206(CHEMBL4757890)
Affinity DataEC50:  708nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563207(CHEMBL4755289)
Affinity DataEC50:  230nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563208(CHEMBL4748601)
Affinity DataEC50:  37nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRelaxin receptor 1(Homo sapiens (Human))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50563209(CHEMBL4777259)
Affinity DataEC50:  17nMAssay Description:Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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