Compile Data Set for Download or QSAR
maximum 50k data
Found 46 with Last Name = 'fitzsimmons' and Initial = 'b'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000534(2-Phenethyl-6-[3-(pyridin-4-ylsulfanyl)-propyl]-2,...)
Affinity DataIC50:  8nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000536(6-Allyl-2-phenethyl-2,3-dihydro-benzofuran-5-ol | ...)
Affinity DataIC50:  17nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280965(4-Phenyl-7-(5-phenyl-pyridin-2-ylmethoxy)-3H-napht...)
Affinity DataIC50:  22nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000526(2-Phenethyl-6-(3-phenoxy-propyl)-2,3-dihydro-benzo...)
Affinity DataIC50:  23nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000551(4-Allyl-2-phenethyl-2,3-dihydro-benzofuran-5-ol | ...)
Affinity DataIC50:  25nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000531(2-(4-Methoxy-benzyl)-3-methyl-6-propyl-2,3-dihydro...)
Affinity DataIC50:  35nMAssay Description:The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000535(3,3-Dimethyl-2-phenethyl-6-(3-phenoxy-propyl)-2,3-...)
Affinity DataIC50:  40nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280968(4-(3-Methoxy-phenyl)-3H-naphtho[2,3-c]furan-1-one ...)
Affinity DataIC50:  42nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000538(3,3-Dimethyl-6-propyl-2-[2-(pyridin-2-ylsulfanyl)-...)
Affinity DataIC50:  44nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000542(4-[3-(5-Hydroxy-2-phenethyl-2,3-dihydro-benzofuran...)
Affinity DataIC50:  44nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000537(2-Phenethyl-4-propyl-6-{3-[4-(5H-tetrazol-5-yl)-ph...)
Affinity DataIC50:  45nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000527(6-[3-(Benzothiazol-2-ylsulfanyl)-propyl]-2-pheneth...)
Affinity DataIC50:  45nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000533(6-Benzyl-2-phenethyl-2,3-dihydro-benzofuran-5-ol |...)
Affinity DataIC50:  48nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000545(8-[3-(5-Hydroxy-2-phenethyl-2,3-dihydro-benzofuran...)
Affinity DataIC50:  50nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000552(2-[2-(4-Chloro-phenyl)-ethyl]-6-(3-phenoxy-propyl)...)
Affinity DataIC50:  51nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000524(6-Allyl-2-[2-(4-methoxy-phenyl)-ethyl]-3,3-dimethy...)
Affinity DataIC50:  52nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000528(1-{2-Hydroxy-4-[3-(5-hydroxy-2-phenethyl-2,3-dihyd...)
Affinity DataIC50:  53nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280961(9-Benzo[1,3]dioxol-5-yl-8H-furo[3',4':6,7]naphtho[...)
Affinity DataIC50:  70nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM32020(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)
Affinity DataIC50:  85nMAssay Description:The compound was tested for its inhibitory activity against LTB4 in human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280963(4-Phenyl-7-(quinolin-2-ylmethoxy)-3H-naphtho[2,3-c...)
Affinity DataIC50:  88nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000544(3,3-Dimethyl-2-[2-(4-methylsulfanyl-phenyl)-ethyl]...)
Affinity DataIC50:  92nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280959(7-Benzyloxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one ...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000525(2-Phenethyl-6-(3-phenoxy-propyl)-4-propyl-2,3-dihy...)
Affinity DataIC50:  127nMAssay Description:The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280979(9-Phenyl-8H-furo[3',4':6,7]naphtho[2,3-d][1,3]diox...)
Affinity DataIC50:  160nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000532(6-Allyl-2-(4-methoxy-benzyl)-3,3-dimethyl-2,3-dihy...)
Affinity DataIC50:  164nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280962(7-Methoxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one | ...)
Affinity DataIC50:  180nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280974(5-Benzo[1,3]dioxol-5-yl-6,8-dihydro-furo[3',4':6,7...)
Affinity DataIC50:  230nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280966(4-Phenyl-3H-naphtho[2,3-c]furan-1-one | CHEMBL6189...)
Affinity DataIC50:  250nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280976(5-Benzo[1,3]dioxol-5-yl-6,7-dimethyl-naphtho[2,3-d...)
Affinity DataIC50:  250nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280971(5-Benzo[1,3]dioxol-5-yl-8H-furo[3',4':6,7]naphtho[...)
Affinity DataIC50:  250nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  320nMAssay Description:The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280970(4-Benzo[1,3]dioxol-5-yl-3H-naphtho[2,3-c]furan-1-o...)
Affinity DataIC50:  380nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280967(5-Benzo[1,3]dioxol-5-yl-5,9-dihydro-furo[3',4':6,7...)
Affinity DataIC50:  420nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280977(4-Phenyl-5H-6-oxa-1-thia-s-indacen-7-one | CHEMBL6...)
Affinity DataIC50:  450nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280961(9-Benzo[1,3]dioxol-5-yl-8H-furo[3',4':6,7]naphtho[...)
Affinity DataIC50:  500nMAssay Description:Compound was evaluated in vitro for inhibition of human recombinant 5-lipoxygenase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280964(5-Benzo[1,3]dioxol-5-yl-furo[3',4':6,7]naphtho[2,3...)
Affinity DataIC50:  660nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280978(6-Methoxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one | ...)
Affinity DataIC50:  670nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50240576(4-Benzo[1,3]dioxol-5-yl-6,7-dimethoxy-3H-naphtho[2...)
Affinity DataIC50:  760nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280973(4-(4-Methoxy-phenyl)-3H-naphtho[2,3-c]furan-1-one ...)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50000546(3,4,5,6-Tetrahydroxy-tetrahydro-pyran-2-carboxylic...)
Affinity DataIC50: >2.00E+3nMAssay Description:The compound was tested for its inhibitory activity against LTB4 in human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280975((5-Benzo[1,3]dioxol-5-yl-7-hydroxymethyl-naphtho[2...)
Affinity DataIC50:  2.20E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280959(7-Benzyloxy-4-phenyl-3H-naphtho[2,3-c]furan-1-one ...)
Affinity DataIC50:  3.00E+3nMAssay Description:Compound was evaluated in vitro for inhibition of human recombinant lipoxygenase enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280969(4-Phenyl-3H-furo[3,4-g]isoquinolin-1-one | CHEMBL3...)
Affinity DataIC50:  3.80E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280972(4-Pyridin-4-yl-3H-naphtho[2,3-c]furan-1-one | CHEM...)
Affinity DataIC50: >4.00E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280980(9-Benzo[1,3]dioxol-5-yl-7,8-dihydro-1,3-dioxa-7-az...)
Affinity DataIC50:  4.20E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280960(9-(3,4-Dimethoxy-phenyl)-8H-furo[3',4':6,7]naphtho...)
Affinity DataIC50: >5.00E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article