TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:The compound was tested for its inhibitory activity against LTB4 in human PMNMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 127nMAssay Description:The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 164nMAssay Description:Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Compound was evaluated in vitro for inhibition of human recombinant 5-lipoxygenase enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: >2.00E+3nMAssay Description:The compound was tested for its inhibitory activity against LTB4 in human PMNMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was evaluated in vitro for inhibition of human recombinant lipoxygenase enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytesMore data for this Ligand-Target Pair