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Found 28 with Last Name = 'flavin' and Initial = 'mt'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50002662((+)-calanolide A | (+)-calnolide A | (10R,11S,12S)...)
Affinity DataIC50:  380nMAssay Description:Inhibitory activity against DNA -dependent DNA polymerase(DDDP) of HIV-1 RT Nucleic Acid polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50002662((+)-calanolide A | (+)-calnolide A | (10R,11S,12S)...)
Affinity DataIC50:  380nMAssay Description:Inhibitory activity against DNA -dependent DNA polymerase(DDDP) of HIV-1 RT Nucleic Acid polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50050430((10S,12S)-12-Hydroxy-6,6,10,11-tetramethyl-4-propy...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against DNA -dependent DNA polymerase(DDDP) of HIV-1 RT Nucleic Acid polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50050430((10S,12S)-12-Hydroxy-6,6,10,11-tetramethyl-4-propy...)
Affinity DataIC50:  970nMAssay Description:Inhibitory activity against RNA-dependent DNA polymerase(RDDP) of HIV-1 RT Nucleic Acid polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226536(CHEMBL98190)
Affinity DataIC50:  2.00E+3nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50002662((+)-calanolide A | (+)-calnolide A | (10R,11S,12S)...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibitory activity against TIBO-resistant HIV-1 RT Nucleic Acid polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50050430((10S,12S)-12-Hydroxy-6,6,10,11-tetramethyl-4-propy...)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibitory activity against TIBO-resistant HIV-1 RT Nucleic Acid polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50226537(CHEMBL319799)
Affinity DataIC50:  1.90E+4nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50050431((-)-calanolide B | (10S,11R,12S)-12-Hydroxy-6,6,10...)
Affinity DataIC50:  2.78E+4nMAssay Description:Inhibitory activity against RNA-dependent DNA polymerase(RDDP) of HIV-1 RT Nucleic Acid polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50323214(6-[4-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-phenoxy...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50323212(6-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydro...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50478418(Agathisflavone | CHEBI:2512)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50478419((+)-Morelloflavone | Morelloflavone)
Affinity DataIC50:  1.16E+5nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50129952(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50050431((-)-calanolide B | (10S,11R,12S)-12-Hydroxy-6,6,10...)
Affinity DataIC50:  1.56E+5nMAssay Description:Inhibitory activity against DNA -dependent DNA polymerase(DDDP) of HIV-1 RT Nucleic Acid polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50478421(CHEMBL445452)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50368352(Cerubidine | DAUNORUBICIN)
Affinity DataIC50:  2.36E+5nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50478420(CHEMBL456859)
Affinity DataIC50:  2.36E+5nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  4.43E+5nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase p66/p51 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50002665((10R,11S)-6,6,10,11-Tetramethyl-4-propyl-10,11-dih...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50002662((+)-calanolide A | (+)-calnolide A | (10R,11S,12S)...)
Affinity DataEC50:  320nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057014((10R,12R)-12-Hydroxy-6,6,10,11,11-pentamethyl-4-pr...)
Affinity DataEC50:  3.20E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50054452((10R,11R)-6,6,10,11-Tetramethyl-4-propyl-10,11-dih...)
Affinity DataEC50:  4.00E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057028((11S,12S)-12-Hydroxy-6,6,11-trimethyl-4-propyl-11,...)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057037((11R,12R)-12-Hydroxy-6,6,10,10,11-pentamethyl-4-pr...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057029((10R,11S,12S)-10-Ethyl-12-hydroxy-6,6,11-trimethyl...)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50057030((10R,11S,12R)-10-Ethyl-12-hydroxy-6,6,11-trimethyl...)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using a poly(rC):oligo(dG)12-18 template primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed