TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 0.00400nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: >7nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibitory constant of the compound was tested angiotensin converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Tested for inhibitory activity against bovine cathepsin B.More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: >300nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: >300nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Tested for inhibitory activity against calpainMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Binding affinity of the compound against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 5.60E+4nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+5nMAssay Description:Binding affinity of the compound against neutral endopeptidaseMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibitory concentration of the compound against rabbit lung Angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair