Found 313 with Last Name = 'furuya' and Initial = 't' TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 0.205nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenateMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 0.499nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenateMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 0.840nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenateMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenateMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenateMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 7.10nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenateMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenateMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel from rat brain cortex homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:The optimized protocol was validated by employing reference compounds such as Cilengitide (+Vβ3/αVβ5−VN interaction) and CWHM12 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics
Curated by ChEMBL
Entasis Therapeutics
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 1.40nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 5.69nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 5.92nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 7.64nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 8nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 8nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
Affinity DataIC50: 8.25nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 9nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
Affinity DataIC50: 9.28nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 9.57nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 9.97nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 10nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
Affinity DataIC50: 11.6nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 11.6nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 13.2nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Pharmadesign
Curated by ChEMBL
Pharmadesign
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of ASK1 assessed as phosphorylated fluorescent peptide by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14.8nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Pharmadesign
Curated by ChEMBL
Pharmadesign
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of ASK1 assessed as phosphorylated fluorescent peptide by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16.9nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 17.5nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 17.6nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 18.2nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Pharmadesign
Curated by ChEMBL
Pharmadesign
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of ASK1 assessed as phosphorylated fluorescent peptide by mobility shift assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 20nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 20nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
Affinity DataIC50: 21.4nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 34.4nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 35.4nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics
Curated by ChEMBL
Entasis Therapeutics
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics
Curated by ChEMBL
Entasis Therapeutics
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Entasis Therapeutics
Curated by ChEMBL
Entasis Therapeutics
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Displacement of fluorescent ligand from Pseudomonas aeruginosa LpxC measured after 30 mins by fluorescence anisotrophy assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Scifluor Life Sciences
US Patent
Scifluor Life Sciences
US Patent
Affinity DataIC50: 50nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
Affinity DataIC50: 50.3nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Affinity DataIC50: 50.4nMAssay Description:The optimized protocol was validated by employing reference compounds such as Cilengitide (+Vβ3/αVβ5−VN interaction) and CWHM12 ...More data for this Ligand-Target Pair
