Affinity DataKi: 0.00528nMAssay Description:The compound was tested for its inhibitory activity against Dihydrofolate reductase derived from L1210 cells.More data for this Ligand-Target Pair
Affinity DataKi: 0.00585nMAssay Description:The compound was tested for its inhibitory activity against dihydrofolate reductase(DHFR) derived from L1210 cells.More data for this Ligand-Target Pair
Affinity DataKi: 0.00687nMAssay Description:The compound was tested for its inhibitory activity against dihydrofolate reductase(DHFR) derived from L1210 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Compound was tested for its inhibitory activity on Recombinant Human Dihydrofolate Reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of pure human thymidyllate synthase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of thymidyllate synthase in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory activity of the compound towards dihydrofolate reductase in L1210 murine leukemia cell linesMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of GAR formyltransferase in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of pure human thymidyllate synthase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibitory activity of the compound towards dihydrofolate reductase in L1210 murine leukemia cell linesMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibitory activity of the compound towards dihydrofolate reductase in L1210 murine leukemia cell linesMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:The compound was tested for its inhibitory activity against thymidylate synthase(TS) derived from H35F/F cells.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of thymidyllate synthase in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibitory activity of the compound towards dihydrofolate reductase in L1210 murine leukemia cell linesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:The compound was tested for its inhibitory activity against thymidylate synthase(TS) derived from K562 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:The compound was tested for its inhibitory activity (IC50) against thymidylate synthase(TS) derived from L. caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of dihydrofolate reductase in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of purified human thymidylate synthase from a SV40-transformed human fibroblast cell line cloned in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of purified human thymidylate synthase from a SV40-transformed human fibroblast cell line cloned in Escherichia coliMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University Of South Alabama
Curated by ChEMBL
University Of South Alabama
Curated by ChEMBL
Affinity DataIC50: >1.70E+4nMAssay Description:Inhibition of GAR formyltransferase in Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
University Of South Alabama
Curated by ChEMBL
University Of South Alabama
Curated by ChEMBL
Affinity DataIC50: >1.70E+4nMAssay Description:Inhibition of thymidyllate synthase in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of dihydrofolate reductase in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of dihydrofolate reductase in Lactobacillus caseiMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University of South Alabama
Curated by ChEMBL
University of South Alabama
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
University Of South Alabama
Curated by ChEMBL
University Of South Alabama
Curated by ChEMBL
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of AICAR formyltransferase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
University Of South Alabama
Curated by ChEMBL
University Of South Alabama
Curated by ChEMBL
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of AICAR formyltransferase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University of South Alabama
Curated by ChEMBL
University of South Alabama
Curated by ChEMBL
Affinity DataIC50: 1.18E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University of South Alabama
Curated by ChEMBL
University of South Alabama
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University of South Alabama
Curated by ChEMBL
University of South Alabama
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University of South Alabama
Curated by ChEMBL
University of South Alabama
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Compound was evaluated for the inhibition of Folyl-polyglutamate synthase in CCRF-CEM Human leukemia cell.More data for this Ligand-Target Pair