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Found 210 with Last Name = 'garofalo' and Initial = 'b'
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518949(CHEMBL4448131)
Affinity DataIC50:  8nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186202(US9163013, 19)
Affinity DataIC50:  10nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186195(US9163013, 12)
Affinity DataIC50:  10nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186204(US9163013, 21)
Affinity DataIC50:  10nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50359538(CHEMBL1235773)
Affinity DataIC50:  14nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186200(US9163013, 17)
Affinity DataIC50:  20nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518919(CHEMBL4575906)
Affinity DataIC50:  20nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in enzyme-mediated supercoiling of relaxed plasmid by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518915(CHEMBL4583368)
Affinity DataIC50:  20nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518940(CHEMBL4541988)
Affinity DataIC50:  20nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186203(US9163013, 20)
Affinity DataIC50:  20nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518915(CHEMBL4583368)
Affinity DataIC50:  40nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518948(CHEMBL4574863)
Affinity DataIC50:  40nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50:  47nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518940(CHEMBL4541988)
Affinity DataIC50:  50nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518948(CHEMBL4574863)
Affinity DataIC50:  100nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518948(CHEMBL4574863)
Affinity DataIC50: <100nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50359538(CHEMBL1235773)
Affinity DataIC50:  100nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518915(CHEMBL4583368)
Affinity DataIC50:  100nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518948(CHEMBL4574863)
Affinity DataIC50: <100nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518915(CHEMBL4583368)
Affinity DataIC50:  100nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518940(CHEMBL4541988)
Affinity DataIC50:  100nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518949(CHEMBL4448131)
Affinity DataIC50:  125nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186190(US9163013, 7)
Affinity DataIC50:  130nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518921(CHEMBL4531538)
Affinity DataIC50:  140nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518924(CHEMBL4533152)
Affinity DataIC50:  150nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186191(US9163013, 8)
Affinity DataIC50:  170nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518924(CHEMBL4533152)
Affinity DataIC50:  200nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186205(US9163013, 22)
Affinity DataIC50:  210nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186192(US9163013, 9)
Affinity DataIC50:  210nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186197(US9163013, 14)
Affinity DataIC50:  230nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186198(US9163013, 15)
Affinity DataIC50:  260nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518911(CHEMBL4530328)
Affinity DataIC50:  300nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186201(US9163013, 18)
Affinity DataIC50:  300nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518924(CHEMBL4533152)
Affinity DataIC50:  300nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186193(US9163013, 10)
Affinity DataIC50:  310nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186210(US9163013, 27)
Affinity DataIC50:  310nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186186(US9163013, 3)
Affinity DataIC50:  310nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186213(US9163013, 30)
Affinity DataIC50:  310nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186212(US9163013, 29)
Affinity DataIC50:  320nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186206(US9163013, 23)
Affinity DataIC50:  330nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186188(US9163013, 5)
Affinity DataIC50:  350nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186184(US9163013, 1)
Affinity DataIC50:  350nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186194(US9163013, 11)
Affinity DataIC50:  360nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186199(US9163013, 16)
Affinity DataIC50:  360nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518911(CHEMBL4530328)
Affinity DataIC50:  400nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA topoisomerase 4 subunit ParC assessed as reduction in decatenation of kinetoplast DNA incubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518940(CHEMBL4541988)
Affinity DataIC50:  400nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186189(US9163013, 6)
Affinity DataIC50:  400nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186207(US9163013, 24)
Affinity DataIC50:  400nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F.

US Patent
LigandPNGBDBM186211(US9163013, 28)
Affinity DataIC50:  450nMT: 2°CAssay Description:Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518939(CHEMBL4531900)
Affinity DataIC50:  500nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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