Affinity DataIC50: 1nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 6 receptor in humanMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against rat dihydroorotate dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor expressed in NG 108 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 4 receptor in guinea pigMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against rat dihydroorotate dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 6 receptor in humanMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor stably expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 6 receptor in humanMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]-LSD binding to cloned h5-HT6 receptors stably expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor in calfMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 127nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 131nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 134nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 134nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 156nMAssay Description:Inhibitory activity against mouse dihydroorotate dehydrogenaseMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc
Curated by ChEMBL
4Sc
Curated by ChEMBL
Affinity DataIC50: 173nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair