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Found 319 with Last Name = 'gazit' and Initial = 'a'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4363((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethio...)
Affinity DataKi:  850nM IC50:  2.40E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4341(2-[(3,4,5-trihydroxyphenyl)methylidene]propanedini...)
Affinity DataKi:  1.00E+3nM IC50:  3.00E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4340((3,4-Dihydroxy-5-methoxybenzylidene)malononitrile ...)
Affinity DataKi:  2.20E+3nM ΔG°:  -32.0kJ/mole IC50:  6.00E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4301((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide...)
Affinity DataKi:  3.50E+3nM IC50:  1.00E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4360((3,4,5,B-Tetrahydroxybenzylidene)malononitrile | 2...)
Affinity DataKi:  4.50E+3nM IC50:  1.35E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4338((3,5-Dihydroxybenzylidene)malononitrile | 2-[(3,5-...)
Affinity DataKi:  1.00E+4nM ΔG°:  -28.3kJ/mole IC50:  3.70E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4339((3,4-Dihydroxybenzylidene)malononitrile | 2-[(3,4-...)
Affinity DataKi:  1.10E+4nM ΔG°:  -28.0kJ/mole IC50:  3.50E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4337(2-[(4-formylphenyl)methylidene]propanedinitrile | ...)
Affinity DataKi:  2.00E+4nM ΔG°:  -26.6kJ/mole IC50:  6.00E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4380((2Z)-2-cyano-3-(2,5-dihydroxyphenyl)prop-2-enoic a...)
Affinity DataKi:  2.40E+4nM IC50:  7.50E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4336(2-[(5-hydroxy-2-nitrophenyl)methylidene]propanedin...)
Affinity DataKi:  2.40E+4nM ΔG°:  -26.1kJ/mole IC50:  9.60E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4352((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic a...)
Affinity DataKi:  2.50E+4nM IC50:  7.00E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4351((2E)-2-cyano-3-(4-formylphenyl)prop-2-enoic acid |...)
Affinity DataKi:  4.70E+4nM IC50:  1.40E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4335(2-[(4-hydroxy-3-nitrophenyl)methylidene]propanedin...)
Affinity DataKi:  4.90E+4nM ΔG°:  -24.4kJ/mole IC50:  1.25E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4334(2-[(3-bromo-4-hydroxy-5-methoxyphenyl)methylidene]...)
Affinity DataKi:  5.00E+4nM ΔG°:  -24.3kJ/mole IC50:  1.53E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4333(2-[(4-hydroxy-3-methoxy-5-nitrophenyl)methylidene]...)
Affinity DataKi:  5.50E+4nM ΔG°:  -24.1kJ/mole IC50:  1.60E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4332(2-[(4-hydroxy-3-methoxyphenyl)methylidene]propaned...)
Affinity DataKi:  6.70E+4nM ΔG°:  -23.6kJ/mole IC50:  2.00E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4330(2-(2H-1,3-benzodioxol-5-ylmethylidene)propanedinit...)
Affinity DataKi:  1.17E+5nM ΔG°:  -22.2kJ/mole IC50:  3.50E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4329(2-[(3-hydroxyphenyl)methylidene]propanedinitrile |...)
Affinity DataKi:  1.23E+5nM ΔG°:  -22.1kJ/mole IC50:  3.75E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4328(4-(2,2-dicyanoeth-1-en-1-yl)benzoic acid | benzyli...)
Affinity DataKi:  1.43E+5nM ΔG°:  -21.7kJ/mole IC50:  4.30E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4326(2-[(3-hydroxy-4-nitrophenyl)methylidene]propanedin...)
Affinity DataKi:  1.50E+5nM ΔG°:  -21.6kJ/mole IC50:  4.50E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4327((2E)-3-[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]prop-2-...)
Affinity DataKi:  1.50E+5nM ΔG°:  -21.6kJ/mole IC50:  4.50E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4325(2-[(3,5-di-tert-butyl-4-hydroxyphenyl)methylidene]...)
Affinity DataKi:  1.55E+5nM ΔG°:  -21.5kJ/mole IC50:  4.60E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4324(2-[(4-hydroxyphenyl)methylidene]propanedinitrile |...)
Affinity DataKi:  1.60E+5nM ΔG°:  -21.4kJ/mole IC50:  5.60E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4350((2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid ...)
Affinity DataKi:  1.65E+5nM IC50:  3.08E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4321(3-{[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]carbamoyl}p...)
Affinity DataKi:  2.40E+5nM ΔG°:  -20.5kJ/mole IC50:  6.40E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4322((4-Morpholinobenzylidene)malononitrile | 2-{[4-(mo...)
Affinity DataKi: >2.50E+5nM ΔG°: >-20.4kJ/mole IC50: >6.25E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4349((2E)-2-cyano-3-(4-hydroxy-3,5-dimethoxyphenyl)prop...)
Affinity DataKi:  2.64E+5nM IC50:  7.00E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4320(2-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]prop...)
Affinity DataKi:  3.00E+5nM ΔG°:  -19.9kJ/mole IC50:  8.50E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4348((2E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)prop-2-e...)
Affinity DataKi:  3.25E+5nM IC50:  8.00E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4354((2E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)but-2-en...)
Affinity DataKi:  3.41E+5nM IC50:  1.10E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4356((2E)-2-cyano-N-(cyanomethyl)-3-(4-hydroxyphenyl)pr...)
Affinity DataKi:  3.60E+5nM IC50:  6.25E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4375((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)
Affinity DataKi:  4.00E+5nM IC50:  1.20E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4319(2-[(4-fluorophenyl)methylidene]propanedinitrile | ...)
Affinity DataKi: >4.00E+5nM ΔG°: >-19.2kJ/mole IC50: >1.25E+6nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4318(2-[(3,5-dimethoxyphenyl)methylidene]propanedinitri...)
Affinity DataKi: >4.00E+5nM ΔG°: >-19.2kJ/mole IC50: >1.25E+6nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4317(2-[(4-methoxyphenyl)methylidene]propanedinitrile |...)
Affinity DataKi: >4.00E+5nM ΔG°: >-19.2kJ/mole IC50: >1.25E+6nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4343((2E)-2-cyano-3-(4-methoxyphenyl)prop-2-enoic acid ...)
Affinity DataKi:  8.33E+5nM IC50:  2.50E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4344((2E)-2-cyano-3-(4-fluorophenyl)prop-2-enoic acid |...)
Affinity DataKi:  8.33E+5nM IC50:  2.50E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4342((2E)-2-cyano-3-phenylprop-2-enoic acid | benzylide...)
Affinity DataKi:  8.50E+5nM IC50: >2.50E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4374((2E)-3-(4-hydroxyphenyl)prop-2-enoic acid | (2E)-3...)
Affinity DataKi:  1.00E+6nM IC50:  3.00E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  16nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM3531(CHEMBL541586 | CHEMBL94431 | N-(3-fluorophenyl)-6,...)
Affinity DataIC50:  90nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4364((3Z)-2-amino-3-[(4-hydroxyphenyl)methylidene]prop-...)
Affinity DataIC50:  125nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036694((E)-2-Cyano-3-(4-hydroxy-3-methoxy-5-phenylsulfany...)
Affinity DataIC50:  130nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036687((E)-3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4403(3-[(6-methylquinazolin-4-yl)amino]benzamide | 4-An...)
Affinity DataIC50:  250nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036698((E)-3-[3-(2-Chloro-benzylsulfanylmethyl)-4-hydroxy...)
Affinity DataIC50:  250nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5148((2E)-3-(3-bromo-4,5-dihydroxyphenyl)-N-{3-[(2E)-3-...)
Affinity DataIC50:  340nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036691((E)-3-[3-(Benzothiazol-2-ylsulfanylmethyl)-4-hydro...)
Affinity DataIC50:  350nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4293((2E)-3-(3,4-dihydroxyphenyl)-2-[(3,4-dihydroxyphen...)
Affinity DataIC50:  370nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM5164((2E)-2-{[(1E)-1-cyano-2-(3,4-dihydroxyphenyl)eth-1...)
Affinity DataIC50:  380nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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