Found 157 with Last Name = 'gerwick' and Initial = 'wh' TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
3D Structure (crystal)TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: 8.80nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 11.8nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Affinity DataKi: 16.5nMAssay Description:Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Affinity DataKi: 29.3nMAssay Description:Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 117nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Affinity DataKi: 238nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Affinity DataKi: 347nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
Affinity DataKi: 375nMAssay Description:Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as...More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in CD rat brain membranesMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: 410nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: 470nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 853nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: 860nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 861nMAssay Description:Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: 1.03E+3nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.74E+3nMAssay Description:Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of California Berkeley
Curated by ChEMBL
University Of California Berkeley
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.79E+4nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in CD rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.87E+4nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in CD rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.95E+4nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in CD rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3.92E+4nMAssay Description:Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00900nMAssay Description:Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of human recombinant Cathepsin S assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0170nMAssay Description:Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0810nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0860nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0940nMAssay Description:Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.112nMAssay Description:Inhibition of human recombinant HDAC2 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.119nMAssay Description:Inhibition of human recombinant HDAC2 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.149nMAssay Description:Inhibition of human recombinant Cathepsin B assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
