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Found 189 with Last Name = 'goulet' and Initial = 'jl'
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282554(((R)-1-{(S)-2-[(1-Acetyl-pyrrolidine-2-carbonyl)-a...)
Affinity DataKi:  6.10nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282555(({(S)-2-[(1-Acetyl-pyrrolidine-2-carbonyl)-amino]-...)
Affinity DataKi:  15nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282539(((R)-1-{(S)-2-[(1-Benzoyl-pyrrolidine-2-carbonyl)-...)
Affinity DataKi:  20nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282542(({(S)-2-[(1-Benzoyl-pyrrolidine-2-carbonyl)-amino]...)
Affinity DataKi:  24nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282552(((R)-1-{(S)-2-[2-((S)-Acetylamino)-propionylamino]...)
Affinity DataKi:  42nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282550(CHEMBL283569 | {[(S)-2-Benzyloxycarbonylamino-3-(1...)
Affinity DataKi:  210nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282546(CHEMBL281630 | [((S)-2-Benzyloxycarbonylamino-prop...)
Affinity DataKi:  280nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282553((Benzyloxycarbonylamino-methyl)-[2-((S)-3-methyl-1...)
Affinity DataKi:  280nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282541(((R)-1-Benzyloxycarbonylamino-ethyl)-[2-((S)-3-met...)
Affinity DataKi:  330nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282543(CHEMBL19827 | [(R)-1-((S)-2-Acetylamino-propionyla...)
Affinity DataKi:  340nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282544((S)-4-Benzyloxycarbonylamino-4-({hydroxy-[2-((S)-3...)
Affinity DataKi:  370nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282549(CHEMBL276960 | {[2-(1,3-Dioxo-1,3-dihydro-isoindol...)
Affinity DataKi:  410nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282558(CHEMBL283526 | {[(S)-2-Benzyloxycarbonylamino-3-(4...)
Affinity DataKi:  560nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282545(CHEMBL282043 | [((S)-2-Benzyloxycarbonylamino-3-ca...)
Affinity DataKi:  600nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282551(CHEMBL280144 | [((S)-2-Benzyloxycarbonylamino-3-ph...)
Affinity DataKi:  710nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282559(CHEMBL20696 | [2-((S)-3-Methyl-1-phenylcarbamoyl-b...)
Affinity DataKi:  940nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282548(CHEMBL276572 | [((S)-2-Benzyloxycarbonylamino-hexa...)
Affinity DataKi:  1.30E+3nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282560(CHEMBL21137 | [(2-Benzyloxycarbonylamino-acetylami...)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282557(((R)-1-Benzylamino-ethyl)-[2-((S)-3-methyl-1-pheny...)
Affinity DataKi:  1.90E+3nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282547((Benzylamino-methyl)-[2-((S)-3-methyl-1-phenylcarb...)
Affinity DataKi:  1.90E+3nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282556(CHEMBL282446 | {(R)-1-[2-(1,3-Dioxo-1,3-dihydro-is...)
Affinity DataKi:  2.40E+3nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282554(((R)-1-{(S)-2-[(1-Acetyl-pyrrolidine-2-carbonyl)-a...)
Affinity DataKi:  2.90E+3nMAssay Description:In vitro inhibition of human fibroblast collagenase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282540(CHEMBL20471 | [((S)-6-Amino-2-benzyloxycarbonylami...)
Affinity DataKi:  4.60E+3nMAssay Description:In vitro inhibition of human recombinant stromelysin-1.More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282539(((R)-1-{(S)-2-[(1-Benzoyl-pyrrolidine-2-carbonyl)-...)
Affinity DataKi:  5.10E+3nMAssay Description:In vitro inhibition of human fibroblast collagenase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282541(((R)-1-Benzyloxycarbonylamino-ethyl)-[2-((S)-3-met...)
Affinity DataKi:  7.50E+3nMAssay Description:In vitro inhibition of human fibroblast collagenase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282553((Benzyloxycarbonylamino-methyl)-[2-((S)-3-methyl-1...)
Affinity DataKi:  1.59E+4nMAssay Description:In vitro inhibition of human fibroblast collagenase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301603((S)-3-((S)-1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidi...)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301604((S)-3-((S)-1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidi...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301619((S)-3-((S)-1-(4-(5-(2-aminopyrimidin-4-yl)-1H-benz...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301624((S)-4-methyl-N(S)-4-methyl-N-(naphthalen-1-yl)-3-(...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301607((S)-3-((S)-1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidi...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301605((S)-3-((S)-1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidi...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301594(3-(1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301594(3-(1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301618((S)-3-((S)-1-(4-(5-(3-ethyl-2-oxoimidazolidin-1-yl...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301588((S)-3-((S)-1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidi...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301608(CHEMBL566507 | ethyl 2-((S)-2-((S)-1-(4-(1H-benzo[...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301621((S)-3-((S)-1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidi...)
Affinity DataIC50:  1nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301617((S)-1-ethyl-3-(1-(2-(1-phenylethylamino)pyrimidin-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301587(CHEMBL567885 | rac 3-(1-(4-(1H-benzo[d]imidazol-1-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301616((S)-4-(5-(2-aminopyrimidin-4-yl)-1H-benzo[d]imidaz...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301606((S)-3-((S)-1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidi...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301595(3-(1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301623((S)-N-(1-phenylethyl)-4-(5-(pyridin-4-yl)-1H-benzo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125504(CHEMBL16806 | Methyl-carbamic acid 4-[(2-methoxy-b...)
Affinity DataIC50:  5nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125521(CHEMBL16804 | Propyl-carbamic acid 4-[(2-methoxy-b...)
Affinity DataIC50:  5nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301593((3-((4-(1H-benzo[d]imidazol-1-yl)pyrimidin-2-ylami...)
Affinity DataIC50:  10nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301583(3-(1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  11nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301596(3-(1-(4-(1H-benzo[d]imidazol-1-yl)pyrimidin-2-ylam...)
Affinity DataIC50:  11.8nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125498(Allyl-carbamic acid 4-[(2-methoxy-benzoylamino)-me...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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