Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 276nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of [3H]WIN-35428 from Dopamine transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Z-MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Antiproliferative activity against MDR human HL60R cell lineMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human recombinant HDAC4 using (S)-[5-Acetylamino-1-(2-oxo-4-trifluorometyl-2Hchromen-7-ylcarbamoyl)pentl]carbami acid tert-Butyl Ester ...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat caudate putamenMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Antiproliferative activity against MDR human HL60R cell lineMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of human recombinant HDAC1 using modified Boc-Lys(Ac)-AMC MAL as substrate after 1 hr by fluorescent activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Antiproliferative activity against MDR human HL60R cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Antiproliferative activity against MDR human HL60R cell lineMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Antiproliferative activity against human K562 cell line expressing Bcr-AblMore data for this Ligand-Target Pair