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Found 286 with Last Name = 'guzik' and Initial = 'h'
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50092989(1-[1-(4-Benzenesulfonyl-phenyl)-ethyl]-4-cyclohexy...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM82247(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity towards Dopamine receptor D1 in rat striatal tissue by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50092984(1-{1-[4-(4-Chloro-benzenesulfonyl)-phenyl]-ethyl}-...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50092996(1-Cyclohexyl-4-{1-[4-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50092995(1-Cyclohexyl-4-{1-[4-(toluene-4-sulfonyl)-phenyl]-...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50092319(1-Cyclohexyl-4-{1-[4-(4-methoxy-benzenesulfinyl)-p...)
Affinity DataKi:  1nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50092989(1-[1-(4-Benzenesulfonyl-phenyl)-ethyl]-4-cyclohexy...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184944(CHEMBL382668 | N-[trans-5-(3-cyanophenyl)bicyclo[3...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184925(CHEMBL380509 | N-[trans-5-(4-fluorophenyl)bicyclo[...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184935(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiperazi...)
Affinity DataKi:  2nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184935(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiperazi...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280440(8-Chloro-5-cyclohex-2-enyl-3-methyl-2,3,4,5-tetrah...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards Dopamine receptor D1 in rat striatal tissue by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280435(8-Chloro-5-cyclohex-1-enyl-3-methyl-2,3,4,5-tetrah...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity towards Dopamine receptor D1 in rat striatal tissue by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184928(CHEMBL382140 | N-[trans-5-(3-cyanophenyl)bicyclo[3...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184948(CHEMBL206616 | N-[trans-5-(3-fluorophenyl)bicyclo[...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184923(1-((1S,2R,5S)-5-(3-acetamidophenyl)bicyclo[3.1.0]h...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184919(CHEMBL208025 | N-[trans-5-(3-cyanophenyl)bicyclo[3...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184923(1-((1S,2R,5S)-5-(3-acetamidophenyl)bicyclo[3.1.0]h...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50188320(3-(3-chloro-4-fluorophenyl)-1-((1S,2R,5S)-5-(4-flu...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50164246(1-[(1S,2R,5S)-5-(4-Cyano-phenyl)-bicyclo[3.1.0]hex...)
Affinity DataKi:  2.70nMAssay Description:Inhibition constant for human Melanin concentrating hormone receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50451110(CHEMBL2111540)
Affinity DataKi:  2.70nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50188334(3-(3-chloro-4-fluorophenyl)-1-((1S,2R,5S)-5-(3-met...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184924(1-((1S,2R,5S)-5-(4-cyanophenyl)bicyclo[3.1.0]hexan...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184924(1-((1S,2R,5S)-5-(4-cyanophenyl)bicyclo[3.1.0]hexan...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184921(CHEMBL204881 | N'-[4-fluoro-3-(trifluoromethyl)phe...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184910(CHEMBL206248 | N'-[4-fluoro-3-(trifluoromethyl)phe...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50164246(1-[(1S,2R,5S)-5-(4-Cyano-phenyl)-bicyclo[3.1.0]hex...)
Affinity DataKi:  3nMAssay Description:Inhibition constant for mouse Melanin concentrating hormone receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50164244(3-(3-Chloro-4-fluoro-phenyl)-1-[4-(3-cyano-phenyl)...)
Affinity DataKi:  3nMAssay Description:Inhibition constant for human Melanin concentrating hormone receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50188316(3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiperazi...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280434(8-Chloro-3-methyl-5-propyl-2,3,4,5-tetrahydro-1H-b...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity towards Dopamine receptor D1 in rat striatal tissue by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184926(CHEMBL382177 | N'-(3-chloro-4-fluorophenyl)-N-[tra...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184913(CHEMBL205838 | N-[trans-5-(4-cyano-3-fluorophenyl)...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280443(8-Chloro-5-cyclohepta-2,4,6-trienyl-3-methyl-2,3,4...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity towards Dopamine receptor D1 in rat striatal tissue by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50451110(CHEMBL2111540)
Affinity DataKi:  3.80nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50451110(CHEMBL2111540)
Affinity DataKi:  3.80nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184911(CHEMBL204407 | N-[trans-5-(3-cyano-4-fluorophenyl)...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184949(CHEMBL206503 | N'-(3-chloro-4-fluorophenyl)-N-[tra...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184941(CHEMBL204212 | N'-(3-chloro-4-fluorophenyl)-N-[tra...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50188318(1-((1S,2R,5S)-5-(4-aminophenyl)bicyclo[3.1.0]hexan...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50188329(1-((1S,2R,5S)-5-(4-acetamidophenyl)bicyclo[3.1.0]h...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50092993(1-Cyclohexyl-4-{2,2,2-trifluoro-1-[4-(4-methoxy-be...)
Affinity DataKi:  5nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280441(8-Chloro-5-cyclopent-1-enyl-3-methyl-2,3,4,5-tetra...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity towards Dopamine receptor D1 in rat striatal tissue by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50188317(CHEMBL212922 | methyl 4-((1R,4S,5R)-4-(3-(4-fluoro...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280439(5-Allyl-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity towards Dopamine receptor D1 in rat striatal tissue by [3H]-SCH- 23390 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50164247(3-(3-Chloro-4-fluoro-phenyl)-1-[(1R,3R,6S)-6-(3-cy...)
Affinity DataKi:  5.90nMAssay Description:Inhibition constant for mouse Melanin concentrating hormone receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50092319(1-Cyclohexyl-4-{1-[4-(4-methoxy-benzenesulfinyl)-p...)
Affinity DataKi:  6nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50092996(1-Cyclohexyl-4-{1-[4-(4-methoxy-benzenesulfonyl)-p...)
Affinity DataKi:  6nMAssay Description:Binding affinity towards the cloned human Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50188321(3-(3-chloro-4-fluorophenyl)-1-((1S,2R,5S)-5-(3-(cy...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184929(CHEMBL204161 | N'-(3-chloro-4-fluorophenyl)-N-[tra...)
Affinity DataKi:  7nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50184937(CHEMBL382631 | N-[trans-5-(3-cyanophenyl)bicyclo[3...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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