TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 0.900nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 4.10nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 6.40nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 6.70nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 11.8nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 18.4nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 24nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 34.6nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 38nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 38.8nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Ono Pharmaceutical
US Patent
Ono Pharmaceutical
US Patent
Affinity DataKi: 42nMAssay Description:The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 485nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184V)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184I)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184V)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 2.07E+3nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184I)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 2.88E+3nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
Instituto De Qu£Mica M£Dica
Curated by ChEMBL
Instituto De Qu£Mica M£Dica
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Binding affinity to recombinant Trypanosoma brucei brucei 427 alternative oxidase expressed in Escherichia coli BL21 cells using ubiquinol-1 as subst...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 5.70E+3nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 6.65E+3nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 8.30E+3nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 8.40E+3nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 1.02E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 1.03E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 1.13E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 1.58E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 1.99E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 2.02E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 2.22E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 2.22E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 2.31E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 2.31E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 2.39E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 2.61E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 3.41E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 3.88E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 4.12E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 5.20E+4nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184V)More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Wayne State University School Of Medicine
Curated by ChEMBL
Wayne State University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 7.10E+4nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184I)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 7.35E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 7.60E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 1.02E+5nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: >1.25E+5nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 1.39E+5nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Nagasaki University
Curated by ChEMBL
Nagasaki University
Curated by ChEMBL
Affinity DataKi: 1.42E+5nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair