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Found 300 with Last Name = 'hayward' and Initial = 'nj'
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM12972((2S)-2-[(2S)-2-({[(1R)-1-(4-bromophenyl)ethyl]carb...)
Affinity DataIC50:  6nMAssay Description:Enzyme peptidolytic activities were measured using a fluorogenic reporter group, 7-amido-4-methylcoumarin (AMC). Released AMC was measured at an emis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM12973((2S)-2-({[(1R)-1-(4-bromophenyl)ethyl]carbamoyl}am...)
Affinity DataIC50:  7nMAssay Description:Enzyme peptidolytic activities were measured using a fluorogenic reporter group, 7-amido-4-methylcoumarin (AMC). Released AMC was measured at an emis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM12974((2S)-2-({[(1R)-1-(4-bromophenyl)ethyl]carbamoyl}am...)
Affinity DataIC50:  8nMAssay Description:Enzyme peptidolytic activities were measured using a fluorogenic reporter group, 7-amido-4-methylcoumarin (AMC). Released AMC was measured at an emis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607810(US11691962, Compound 1-208)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607811(US11691962, Compound 1-209)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607812(US11691962, Compound 1-210)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607813(US11691962, Compound 1-211)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607814(US11691962, Compound 1-212)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607815(US11691962, Compound 1-213)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607816(US11691962, Compound 1-214)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607817(US11691962, Compound 1-215)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607818(US11691962, Compound 1-216)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607819(US11691962, Compound 1-217)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607820(US11691962, Compound 1-218)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607821(US11691962, Compound 1-219)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607726(US11691962, Compound 1-124)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607727(US11691962, Compound 1-125)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607729(US11691962, Compound 1-127)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607730(US11691962, Compound 1-128)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607731(US11691962, Compound 1-129)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607732(US11691962, Compound 1-130)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607734(US11691962, Compound 1-132)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607736(US11691962, Compound 1-134)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607737(US11691962, Compound 1-135)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607738(US11691962, Compound 1-136)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607739(US11691962, Compound 1-137)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607740(US11691962, Compound 1-138)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607742(US11691962, Compound 1-140)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607743(US11691962, Compound 1-141)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607744(US11691962, Compound 1-142)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607745(US11691962, Compound 1-143)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607746(US11691962, Compound 1-144)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607747(US11691962, Compound 1-145)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607748(US11691962, Compound 1-146)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607749(US11691962, Compound 1-147)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607752(US11691962, Compound 1-150)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607753(US11691962, Compound 1-151)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607754(US11691962, Compound 1-152)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607755(US11691962, Compound 1-153)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607756(US11691962, Compound 1-154)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607757(US11691962, Compound 1-155)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607758(US11691962, Compound 1-156)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607760(US11691962, Compound 1-158)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607761(US11691962, Compound 1-159)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607762(US11691962, Compound 1-160)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607763(US11691962, Compound 1-161)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607764(US11691962, Compound 1-162)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607765(US11691962, Compound 1-163)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607766(US11691962, Compound 1-164)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Daiichi Asubio Medical Research Laboratories

LigandPNGBDBM607768(US11691962, Compound 1-166)
Affinity DataIC50: <10nMAssay Description:The ability of compounds of the present invention to inhibit Factor XIa was evaluated by determining the concentration of inhibitor, which resulted i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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