Affinity DataKi: 5.70nMAssay Description:Inhibition of human CA12 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human CA12 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Inhibition of human CA12 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 630nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.15E+3nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.56E+3nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.13E+3nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.51E+3nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.34E+3nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.80E+3nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.20E+3nMAssay Description:Inhibition of human CA12 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.02E+4nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.46E+4nMAssay Description:Inhibition of human CA12 by stopped-flow assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: <0.300nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibitory activity against FKBP12More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of MGLL in human intact PC3 cells preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against FKBP12More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against FKBP12More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibitory activity against FKBP12More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of MGLL derived from mouse brain homogenates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]dofetilide from human ERG by high throughput assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human c-ABL SH3/SH2/SH1 domain (46 to 531 residues) expressed in sf9 insect cells after 30 mins in presence of [gamma-32P]A...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of ABL1 (64 to 515 residues)(unknown origin) expressed in Escherichia coli using FITC-Ahx-EAIYAAPFAKKK-NH2 peptide as substrate after 60 m...More data for this Ligand-Target Pair