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Found 506 with Last Name = 'hirst' and Initial = 'dj'
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50125265(CHEMBL204021 | N-(2-Diethylamino-ethyl)-2-[2-(4-fl...)
Affinity DataIC50:  0.0631nMAssay Description:Inhibition of human recombinant LpPLA2More data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50205805(Rilapladib | SB-659032)
Affinity DataIC50:  0.251nMAssay Description:Inhibition of LpPLA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50205804(CHEMBL3967156)
Affinity DataIC50:  0.398nMAssay Description:Inhibition of human recombinant LpPLA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50547191(CHEMBL4746468)
Affinity DataIC50:  2nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50547190(CHEMBL4762949)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607759(CHEMBL5218813)
Affinity DataIC50:  4nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50547180(CHEMBL4796852)
Affinity DataIC50:  5nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607759(CHEMBL5218813)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50547179(CHEMBL4743507)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50028142(CHEMBL2177300)
Affinity DataIC50:  6.30nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y97A mutant BD2 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607758(CHEMBL5219991)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607761(CHEMBL5221069)
Affinity DataIC50:  10nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607761(CHEMBL5221069)
Affinity DataIC50:  10nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50526962(CHEMBL4448056)
Affinity DataIC50:  10nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607758(CHEMBL5219991)
Affinity DataIC50:  10nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50526964(CHEMBL4438171)
Affinity DataIC50:  13nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607762(CHEMBL5220494)
Affinity DataIC50:  13nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50526964(CHEMBL4438171)
Affinity DataIC50:  13nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50028142(CHEMBL2177300)
Affinity DataIC50:  16nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607762(CHEMBL5220494)
Affinity DataIC50:  16nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607765(CHEMBL5218726)
Affinity DataIC50:  16nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50603088(CHEMBL5203965)
Affinity DataIC50:  20nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 30 mins in presence of fluorescent ligand by TR-FRET methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607769(CHEMBL5219538)
Affinity DataIC50:  20nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607762(CHEMBL5220494)
Affinity DataIC50:  20nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607760(CHEMBL5219194)
Affinity DataIC50:  20nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607758(CHEMBL5219991)
Affinity DataIC50:  20nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607765(CHEMBL5218726)
Affinity DataIC50:  25nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50547187(CHEMBL4791887)
Affinity DataIC50:  25nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50547178(CHEMBL4800438)
Affinity DataIC50:  25nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607759(CHEMBL5218813)
Affinity DataIC50:  25nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607766(CHEMBL5220128)
Affinity DataIC50:  25nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607763(CHEMBL5218817)
Affinity DataIC50:  25nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50526959(CHEMBL4522991)
Affinity DataIC50:  31.6nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50526959(CHEMBL4522991)
Affinity DataIC50:  32nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607766(CHEMBL5220128)
Affinity DataIC50:  32nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607767(CHEMBL5218909)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607768(CHEMBL5219602)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607770(CHEMBL5219919)
Affinity DataIC50:  32nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607770(CHEMBL5219919)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455493(CHEMBL4213809)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607767(CHEMBL5218909)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607760(CHEMBL5219194)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607763(CHEMBL5218817)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607769(CHEMBL5219538)
Affinity DataIC50:  32nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-C motif chemokine 2(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607769(CHEMBL5219538)
Affinity DataIC50:  40nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)
Affinity DataIC50:  40nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50526961(CHEMBL4576013)
Affinity DataIC50:  40nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Mus musculus (Mouse))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50547191(CHEMBL4746468)
Affinity DataIC50:  40nMAssay Description:Inhibition of MetAP2 in mouse B cells assessed as reduction in IgG secretionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607766(CHEMBL5220128)
Affinity DataIC50:  40nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50607757(CHEMBL5218822)
Affinity DataIC50:  40nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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