TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 0.0631nMAssay Description:Inhibition of human recombinant LpPLA2More data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 0.251nMAssay Description:Inhibition of LpPLA2 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human recombinant LpPLA2More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y97A mutant BD2 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 30 mins in presence of fluorescent ligand by TR-FRET methodMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of MetAP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 31.6nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of MetAP2 in mouse B cells assessed as reduction in IgG secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair