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Found 57 with Last Name = 'hoeglund' and Initial = 'ab'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50148348((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)
Affinity DataKi:  100nMAssay Description:Noncompetitive type inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300224(4-amino-4-(hydroxymethyl)-6-(4-octylphenyl)hexylph...)
Affinity DataKi:  200nMAssay Description:Noncompetitive type inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300212(2-(4-{[(3-Trifluoromethylphenyl)amino]carbonothioy...)
Affinity DataKi:  700nMAssay Description:Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataKi:  1.90E+3nMAssay Description:Competitive-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataKi:  1.90E+3nMAssay Description:Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300210(2-(4-{[(3-Chlorophenyl)amino]carbonothioyl}-1-pipe...)
Affinity DataKi:  2.60E+3nMAssay Description:Mixed type inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308960(2-(4-((9H-xanthene-9-carbonyl)carbamothioyl)pipera...)
Affinity DataKi:  2.70E+3nMAssay Description:Competitive-type inhibition of autotaxin-mediated pNP-TMP hydrolysis by Michaelis-Menton analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308960(2-(4-((9H-xanthene-9-carbonyl)carbamothioyl)pipera...)
Affinity DataKi:  2.70E+3nMAssay Description:Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300209(2-(4-{[(2,5-Dichlorophenyl)amino]carbonothioyl}-1-...)
Affinity DataKi:  3.40E+3nMAssay Description:Mixed type inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300216(2-(4-{[(3,5-Bis(trifluoromethyl)phenyl)amino]carbo...)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300221(2-(4-{[(3,5-Dimethylphenyl)amino]carbonothioyl}-1-...)
Affinity DataKi:  4.20E+3nMAssay Description:Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300215(2-(4-{[(3-Methylphenyl)amino]carbonothioyl}-1-pipe...)
Affinity DataKi:  4.50E+3nMAssay Description:Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308959(4,4'-(5,5'-carbonylbis(1,3-dioxoisoindoline-5,2-di...)
Affinity DataKi:  5.00E+3nMAssay Description:Competitive-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300222(2-(4-{[(4-Chlorophenyl)amino]carbonothioyl}-1-pipe...)
Affinity DataKi:  5.70E+3nMAssay Description:Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308958(4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-5-c...)
Affinity DataKi:  5.80E+3nMAssay Description:Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308961(4-(2-(3-ethyl-4-oxo-3,4,6,7,8,9-hexahydropyrimido[...)
Affinity DataKi:  6.50E+3nMAssay Description:Noncompetitive inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataKi:  6.50E+3nMAssay Description:Noncompetitive inhibition of autotaxin-mediated pNP-TMP hydrolysis by Michaelis-Menton analysis for enzyme-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataKi:  6.50E+3nMAssay Description:Noncompetitive inhibition of autotaxin-mediated pNP-TMP hydrolysis by Michaelis-Menton analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300217(2-(4-{[(3-Benzothiadiazolphenyl)amino]carbonothioy...)
Affinity DataKi:  7.10E+3nMAssay Description:Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300220(2-(4-{[(3-Iodophenyl)amino]carbonothioyl}-1-pipera...)
Affinity DataKi:  7.40E+3nMAssay Description:Mixed type inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308961(4-(2-(3-ethyl-4-oxo-3,4,6,7,8,9-hexahydropyrimido[...)
Affinity DataKi:  9.30E+3nMAssay Description:Noncompetitive inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis for enzyme-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300220(2-(4-{[(3-Iodophenyl)amino]carbonothioyl}-1-pipera...)
Affinity DataKi:  1.10E+4nMAssay Description:Mixed type inhibition of human autotaxin at enzyme-substrate complex isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300211(2-(4-{[(4-Iodophenyl)amino]carbonothioyl}-1-pipera...)
Affinity DataKi:  1.32E+4nMAssay Description:Mixed type inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300208(2-(4-{[(4-Trifluoromethylphenyl)amino]carbonothioy...)
Affinity DataKi:  1.32E+4nMAssay Description:Noncompetitive type inhibition of human autotaxin at enzyme-substrate complex isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300208(2-(4-{[(4-Trifluoromethylphenyl)amino]carbonothioy...)
Affinity DataKi:  1.32E+4nMAssay Description:Noncompetitive type inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308957(3-(1,3-dioxo-2-(4-(phenyldiazenyl)phenyl)isoindoli...)
Affinity DataKi:  1.51E+4nMAssay Description:Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308960(2-(4-((9H-xanthene-9-carbonyl)carbamothioyl)pipera...)
Affinity DataKi:  1.98E+4nMAssay Description:Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis for enzyme-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300209(2-(4-{[(2,5-Dichlorophenyl)amino]carbonothioyl}-1-...)
Affinity DataKi:  2.20E+4nMAssay Description:Mixed type inhibition of human autotaxin at enzyme-substrate complex isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308958(4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-5-c...)
Affinity DataKi:  3.23E+4nMAssay Description:Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis for enzyme-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300211(2-(4-{[(4-Iodophenyl)amino]carbonothioyl}-1-pipera...)
Affinity DataKi:  3.41E+4nMAssay Description:Mixed type inhibition of human autotaxin at enzyme-substrate complex isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308957(3-(1,3-dioxo-2-(4-(phenyldiazenyl)phenyl)isoindoli...)
Affinity DataKi:  4.03E+4nMAssay Description:Mixed-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis for enzyme-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300210(2-(4-{[(3-Chlorophenyl)amino]carbonothioyl}-1-pipe...)
Affinity DataKi:  4.73E+4nMAssay Description:Mixed type inhibition of human autotaxin at enzyme-substrate complex isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300212(2-(4-{[(3-Trifluoromethylphenyl)amino]carbonothioy...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of autotaxin-mediated pNP-TMP hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300209(2-(4-{[(2,5-Dichlorophenyl)amino]carbonothioyl}-1-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300208(2-(4-{[(4-Trifluoromethylphenyl)amino]carbonothioy...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308960(2-(4-((9H-xanthene-9-carbonyl)carbamothioyl)pipera...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of autotaxin-mediated FS3 hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308961(4-(2-(3-ethyl-4-oxo-3,4,6,7,8,9-hexahydropyrimido[...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of autotaxin-mediated FS3 hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300220(2-(4-{[(3-Iodophenyl)amino]carbonothioyl}-1-pipera...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of autotaxin-mediated FS3 hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308960(2-(4-((9H-xanthene-9-carbonyl)carbamothioyl)pipera...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of autotaxin-mediated pNP-TMP hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300210(2-(4-{[(3-Chlorophenyl)amino]carbonothioyl}-1-pipe...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300216(2-(4-{[(3,5-Bis(trifluoromethyl)phenyl)amino]carbo...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300211(2-(4-{[(4-Iodophenyl)amino]carbonothioyl}-1-pipera...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308958(4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-5-c...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of autotaxin-mediated pNP-TMP hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50308958(4-(4-(2-(naphthalen-1-yl)-1,3-dioxoisoindoline-5-c...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of autotaxin-mediated FS3 hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300221(2-(4-{[(3,5-Dimethylphenyl)amino]carbonothioyl}-1-...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300222(2-(4-{[(4-Chlorophenyl)amino]carbonothioyl}-1-pipe...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300217(2-(4-{[(3-Benzothiadiazolphenyl)amino]carbonothioy...)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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