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Found 279 with Last Name = 'hofer' and Initial = 'p'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14381(4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl...)
Affinity DataKi:  3nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243005(2-(6-Chloro-2-(4-(2-fluoroethoxy)phenyl)imidazo[1,...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14376(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3,4-me...)
Affinity DataKi:  3.70nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243006(2-(6-Chloro-2-(4-(3-fluoropropoxy)phenyl)imidazo[1...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14365(8-(1-Benzyloxy-1-methyl-ethyl)-3-(3-cyclopentyloxy...)
Affinity DataKi:  4.10nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243008(CHEMBL469682 | N,N-Diethyl-2-(2-(4-(3-fluoropropox...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243006(2-(6-Chloro-2-(4-(3-fluoropropoxy)phenyl)imidazo[1...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14379(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-tert...)
Affinity DataKi:  4.30nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14370(8-{1-[(4-Chlorobenzyl)oxy]-1-methyl-ethyl}-3-[3-cy...)
Affinity DataKi:  4.80nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14382(4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl...)
Affinity DataKi:  4.90nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14379(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-tert...)
Affinity DataKi:  5nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14366(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(2-meth...)
Affinity DataKi:  5.10nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14367(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3-meth...)
Affinity DataKi:  5.10nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14381(4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl...)
Affinity DataKi:  5.20nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14381(4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl...)
Affinity DataKi:  5.5nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243007(2-(2-(4-(2-Fluoroethoxy)phenyl)-5,7-dimethylpyrazo...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14368(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)
Affinity DataKi:  5.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14365(8-(1-Benzyloxy-1-methyl-ethyl)-3-(3-cyclopentyloxy...)
Affinity DataKi:  5.70nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243007(2-(2-(4-(2-Fluoroethoxy)phenyl)-5,7-dimethylpyrazo...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243008(CHEMBL469682 | N,N-Diethyl-2-(2-(4-(3-fluoropropox...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14379(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-tert...)
Affinity DataKi:  5.80nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14370(8-{1-[(4-Chlorobenzyl)oxy]-1-methyl-ethyl}-3-[3-cy...)
Affinity DataKi:  5.80nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50243005(2-(6-Chloro-2-(4-(2-fluoroethoxy)phenyl)imidazo[1,...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14367(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3-meth...)
Affinity DataKi:  6nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Radiopharmaceuticals Research Institute

Curated by ChEMBL
LigandPNGBDBM50217008(CHEMBL230904 | N-(1-(2-fluoroethyl)piperidin-4-yl)...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14385(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1,1-dimet...)
Affinity DataKi:  6.30nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14380(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trif...)
Affinity DataKi:  6.5nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14376(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3,4-me...)
Affinity DataKi:  6.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14386(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1,1-dimet...)
Affinity DataKi:  6.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14369(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)
Affinity DataKi:  6.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14378(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3,4-di...)
Affinity DataKi:  6.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14371(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(2-fluo...)
Affinity DataKi:  6.80nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14385(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1,1-dimet...)
Affinity DataKi:  7nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14366(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(2-meth...)
Affinity DataKi:  7.10nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14380(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trif...)
Affinity DataKi:  7.20nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14372(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3-fluo...)
Affinity DataKi:  7.40nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14369(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)
Affinity DataKi:  7.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14382(4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl...)
Affinity DataKi:  7.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14373((2E)-but-2-enedioic acid; 3-{[3-(cyclopentyloxy)-4...)
Affinity DataKi:  7.80nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14374((2E)-but-2-enedioic acid; 3-{[3-(cyclopentyloxy)-4...)
Affinity DataKi:  7.90nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14382(4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl...)
Affinity DataKi:  8nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14368(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)
Affinity DataKi:  8.10nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14372(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3-fluo...)
Affinity DataKi:  8.40nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14365(8-(1-Benzyloxy-1-methyl-ethyl)-3-(3-cyclopentyloxy...)
Affinity DataKi:  8.90nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14386(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1,1-dimet...)
Affinity DataKi:  9nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14374((2E)-but-2-enedioic acid; 3-{[3-(cyclopentyloxy)-4...)
Affinity DataKi:  9nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14386(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1,1-dimet...)
Affinity DataKi:  9.5nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14378(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3,4-di...)
Affinity DataKi:  9.70nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14369(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)
Affinity DataKi:  9.80nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma

LigandPNGBDBM14384(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trif...)
Affinity DataKi:  9.90nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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