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Found 448 with Last Name = 'hong' and Initial = 'vs'
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataKi:  0.200nMAssay Description:Binding affinity at recombinant Hsp90alpha incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity at recombinant Hsp90alpha incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
TargetEndoplasmin(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataKi:  61nMAssay Description:Binding affinity at Grp94 incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataKi:  255nMAssay Description:Binding affinity at TRAP1 incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451322(CHEMBL4210026)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451338(CHEMBL4207673)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451337(CHEMBL4204601)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401335(CHEMBL2205798)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042863(CHEMBL3354513)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042864(CHEMBL3354514)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451325(CHEMBL4202424)
Affinity DataIC50:  1nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50572947(CHEMBL4871014)
Affinity DataIC50:  1nMAssay Description:Inhibition of human ATX assessed as reduction in LPA formation using FS-3 as substrate preincubated for 30 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451321(CHEMBL4211388)
Affinity DataIC50:  1nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042871(CHEMBL3354521)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042868(CHEMBL3354518)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042863(CHEMBL3354513)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042866(CHEMBL3354516)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042867(CHEMBL3354517)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042868(CHEMBL3354518)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042868(CHEMBL3354518)
Affinity DataIC50:  1nMAssay Description:Inhibition of PIM2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401336(CHEMBL2205245)
Affinity DataIC50:  1nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451314(CHEMBL4207648)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451334(CHEMBL4213138)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50572945(CHEMBL4850429)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human ATX assessed as reduction in LPA formation using FS-3 as substrate preincubated for 30 mins followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451318(CHEMBL4218098)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451328(CHEMBL4211697)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451322(CHEMBL4210026)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of renin in human plasma using angiotensinogen as substrate measured for 90 mins by [125I]-angiotensin based radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451329(CHEMBL4212429)
Affinity DataIC50:  2nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401334(CHEMBL2205799)
Affinity DataIC50:  2nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042861(CHEMBL3354511)
Affinity DataIC50:  2nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042867(CHEMBL3354517)
Affinity DataIC50:  2nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451331(CHEMBL4217145)
Affinity DataIC50:  2nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451319(CHEMBL4212859)
Affinity DataIC50:  2nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451320(CHEMBL4216413)
Affinity DataIC50:  2nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451317(CHEMBL4202961)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50015325(CHEMBL3264258)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of PIM1 kinase (unknown origin) using 5-FAM-labeled BAD peptide as substrate after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50108775(CHEMBL3596638)
Affinity DataIC50:  3nMAssay Description:Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50108782(CHEMBL3596639)
Affinity DataIC50:  3nMAssay Description:Inverse agonist activity at human recombinant GST-tagged RORgammat ligand binding domain assessed as effect on receptor-biotin tagged TRAP220 co-acti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  3nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50015324(CHEMBL3264257)
Affinity DataIC50:  3nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50275337(CHEMBL4129087)
Affinity DataIC50:  3nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50275422(CHEMBL4125914)
Affinity DataIC50:  3nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451340(CHEMBL4214937)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451323(CHEMBL4215302)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451312(CHEMBL4209674)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50451337(CHEMBL4204601)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of renin in human plasma using angiotensinogen as substrate measured for 90 mins by [125I]-angiotensin based radioimmunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50015324(CHEMBL3264257)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of PIM1 kinase (unknown origin) using 5-FAM-labeled BAD peptide as substrate after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50572943(CHEMBL4872157)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human ATX assessed as reduction in LPA formation using FS-3 as substrate preincubated for 30 mins followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401332(CHEMBL2205800)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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