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Found 49 with Last Name = 'horn' and Initial = 'jr'
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50048866(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  2.62nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351992(CHEMBL1822599)
Affinity DataKi:  9.08nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351993(CHEMBL1822600)
Affinity DataKi:  19.8nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351990(CHEMBL1822597)
Affinity DataKi:  78.7nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351991(CHEMBL1822598)
Affinity DataKi:  96.2nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351988(CHEMBL1822595)
Affinity DataKi:  2.57E+3nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50351989(CHEMBL1822596)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50437324(CHEMBL2407597)
Affinity DataIC50:  9nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM76305(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
Affinity DataIC50:  55nMAssay Description:Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM64987(5-nitro-8-quinolinol | 5-nitroquinolin-8-ol | 8-HY...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM32203(8-quinolinol | CHEMBL310555 | US10005735, Table 1....)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM76305(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM32203(8-quinolinol | CHEMBL310555 | US10005735, Table 1....)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50437326(CHEMBL2407599)
Affinity DataIC50:  2.66E+3nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50437325(CHEMBL1368981)
Affinity DataIC50:  3.81E+3nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50437327(CHEMBL2023325)
Affinity DataIC50:  7.68E+3nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM32203(8-quinolinol | CHEMBL310555 | US10005735, Table 1....)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM76305(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM64987(5-nitro-8-quinolinol | 5-nitroquinolin-8-ol | 8-HY...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50211290(CHEMBL2407096)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50211290(CHEMBL2407096)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM76305(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50437328(CHEMBL2407598)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM32203(8-quinolinol | CHEMBL310555 | US10005735, Table 1....)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50437328(CHEMBL2407598)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50065785(2-Methyl-quinolin-8-ol | CHEMBL316892)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human methionine aminopeptidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50502707(CHEMBL4458954)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of Salmonella typhimurium IspF by malachite green dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50502708(CHEMBL3222163)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of Salmonella typhimurium IspF by malachite green dye based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50437326(CHEMBL2407599)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50437327(CHEMBL2023325)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50437325(CHEMBL1368981)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM31916(Tryptophanhydroxamate, 13)
Affinity DataKd:  8.48E+5nMAssay Description:Binding affinity to Burkholderia pseudomallei IspF at pH 6 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50443772(CHEMBL1230597)
Affinity DataKd:  1.80E+5nMAssay Description:Binding affinity to Burkolderia pseudomallei IspF by surface plasmon resonance methodMore data for this Ligand-Target Pair
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM31916(Tryptophanhydroxamate, 13)
Affinity DataKd:  2.40E+4nMAssay Description:Binding affinity to Burkholderia pseudomallei IspF at pH 8 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50443771(CHEMBL3094103)
Affinity DataKd:  1.48E+5nMAssay Description:Binding affinity to Burkolderia pseudomallei IspF by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50443773(CHEMBL1230528)
Affinity DataKd:  1.35E+5nMAssay Description:Binding affinity to Burkolderia pseudomallei IspF by surface plasmon resonance methodMore data for this Ligand-Target Pair
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM31916(Tryptophanhydroxamate, 13)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to Escherichia coli IspF at pH 7.4 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50443770(CHEMBL3094104)
Affinity DataKd:  7.00E+4nMAssay Description:Binding affinity to Burkolderia pseudomallei IspF by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50443774(CHEMBL3094106)
Affinity DataKd:  9.00E+4nMAssay Description:Binding affinity to Burkolderia pseudomallei IspF by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50194153(5'-CDP | CDP | CHEMBL425252 | Cytidine | Cytidine ...)
Affinity DataKd:  7.50E+4nMAssay Description:Binding affinity to Burkolderia pseudomallei IspF by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50043799((2R)-2-amino-3-(1H-indol-3-yl)propanoic acid | (R)...)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to Burkholderia pseudomallei IspF at pH 7.4 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM21974((2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | CHE...)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to Burkholderia pseudomallei IspF at pH 7.4 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50443775(CHEMBL3094105)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to Burkolderia pseudomallei IspF by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM31916(Tryptophanhydroxamate, 13)
Affinity DataKd:  3.60E+4nMAssay Description:Binding affinity to Burkholderia pseudomallei IspF at pH 7.4 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM50566954(CHEMBL4874588)
Affinity DataKd:  6.40E+4nMAssay Description:Binding affinity to Burkholderia pseudomallei IspF at pH 7.4 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed