Compile Data Set for Download or QSAR
maximum 50k data
Found 81 with Last Name = 'huebert' and Initial = 'nd'
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50123504(CHEMBL142546 | N-((6-amino-2-methylpyridin-3-yl)me...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377618(CHEMBL254353)
Affinity DataKi:  0.380nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377625(CHEMBL254557)
Affinity DataKi:  0.570nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377615(CHEMBL254962)
Affinity DataKi:  0.650nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377623(CHEMBL254759)
Affinity DataKi:  0.660nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377611(CHEMBL258018)
Affinity DataKi:  0.770nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377619(CHEMBL402758)
Affinity DataKi:  0.790nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377622(CHEMBL257543)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377620(CHEMBL254784)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377614(CHEMBL401655)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377617(CHEMBL403359)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377624(CHEMBL403310)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11123((2S)-1-[(2S)-2-amino-3-[4-(2,4-difluorophenyl)phen...)
Affinity DataKi:  2.20nM ΔG°:  -49.4kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377607(CHEMBL404025)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377626(CHEMBL254786)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11121((2S)-1-[(2S)-2-amino-3-[4-(4-fluorophenyl)phenyl]p...)
Affinity DataKi:  3.10nM ΔG°:  -48.6kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377616(CHEMBL258198)
Affinity DataKi:  3.20nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50149023(3-{[1-({[(diaminomethylidene)amino]oxy}methyl)cycl...)
Affinity DataKi:  4nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50149023(3-{[1-({[(diaminomethylidene)amino]oxy}methyl)cycl...)
Affinity DataKi:  4nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377608(CHEMBL256941)
Affinity DataKi:  4nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11122((2S)-1-[(2S)-2-amino-3-[4-(2-fluorophenyl)phenyl]p...)
Affinity DataKi:  5.30nM ΔG°:  -47.2kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377613(CHEMBL258225)
Affinity DataKi:  9nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377621(CHEMBL254785)
Affinity DataKi:  10nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377612(CHEMBL255916)
Affinity DataKi:  11nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11118((2S)-1-[(2S)-2-amino-3-(4-phenylphenyl)propanoyl]p...)
Affinity DataKi:  13nM ΔG°:  -45.0kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377609(CHEMBL256091)
Affinity DataKi:  19nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11119((2S)-1-[(2S)-2-amino-3-[4-(4-methylphenyl)phenyl]p...)
Affinity DataKi:  20nM ΔG°:  -43.9kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11120((2S)-1-[(2S)-2-amino-3-[4-(3,4-dimethoxyphenyl)phe...)
Affinity DataKi:  26nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11113(6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...)
Affinity DataKi:  27nM ΔG°:  -43.2kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377610(CHEMBL250551)
Affinity DataKi:  33nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11116((2S)-1-[(2S)-2-amino-3-(4-iodophenyl)propanoyl]pyr...)
Affinity DataKi:  34nM ΔG°:  -42.6kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11124((2S)-1-[(2S)-2-amino-3-[4-(furan-2-yl)phenyl]propa...)
Affinity DataKi:  36nM ΔG°:  -42.5kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50223072(CHEMBL401842 | N-[2-(carbamimidamidooxy)ethyl]-2-{...)
Affinity DataKi:  47nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11115((2S)-1-[(2S)-2-amino-3-phenylpropanoyl]pyrrolidine...)
Affinity DataKi:  63nM ΔG°:  -41.1kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11136((2S)-2-amino-3-[4-(2,4-difluorophenyl)phenyl]-1-(1...)
Affinity DataKi:  96nM ΔG°:  -40.1kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11134(4-{4-[(2S)-2-amino-3-oxo-3-(1,3-thiazolidin-3-yl)p...)
Affinity DataKi:  160nM ΔG°:  -38.8kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11133(3-{4-[(2S)-2-amino-3-oxo-3-(1,3-thiazolidin-3-yl)p...)
Affinity DataKi:  166nM ΔG°:  -38.7kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11135((2S)-2-amino-3-[4-(4-fluorophenyl)phenyl]-1-(1,3-t...)
Affinity DataKi:  170nM ΔG°:  -38.6kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11132(4-{4-[(2S)-2-amino-3-oxo-3-(1,3-thiazolidin-3-yl)p...)
Affinity DataKi:  310nM ΔG°:  -37.1kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11131((2S)-2-amino-3-[4-(pyridin-2-yl)phenyl]-1-(1,3-thi...)
Affinity DataKi:  355nM ΔG°:  -36.8kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11125((2S)-2-amino-3-(4-phenylphenyl)-1-(1,3-thiazolidin...)
Affinity DataKi:  360nM ΔG°:  -36.8kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11117(4-[(2S)-2-amino-3-[(2S)-2-cyanopyrrolidin-1-yl]-3-...)
Affinity DataKi:  470nM ΔG°:  -36.1kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11130((2S)-2-amino-3-(4-iodophenyl)-1-(1,3-thiazolidin-3...)
Affinity DataKi:  980nM ΔG°:  -34.3kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11126((2S)-2-amino-3-(4-phenylphenyl)-1-(pyrrolidin-1-yl...)
Affinity DataKi:  1.16E+3nM ΔG°:  -33.9kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11137((2S)-2-amino-3-(naphthalen-2-yl)-1-(1,3-thiazolidi...)
Affinity DataKi:  8.90E+3nM ΔG°:  -28.8kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11129((2S)-2-amino-1-(2,2-dimethyl-1,3-oxazolidin-3-yl)-...)
Affinity DataKi: >1.28E+4nM ΔG°: >-27.9kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11128((2S)-2-amino-1-[(2S)-2-[(benzyloxy)methyl]pyrrolid...)
Affinity DataKi: >1.28E+4nM ΔG°: >-27.9kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11127((2S)-2-amino-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1...)
Affinity DataKi: >1.28E+4nM ΔG°: >-27.9kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11138((2S)-2-amino-3-(naphthalen-1-yl)-1-(1,3-thiazolidi...)
Affinity DataKi: >1.28E+4nM ΔG°: >-27.9kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM11139((2S)-2-amino-3-(1H-indol-3-yl)-1-(1,3-thiazolidin-...)
Affinity DataKi: >1.28E+4nM ΔG°: >-27.9kJ/molepH: 7.4 T: 2°CAssay Description:The progress of DPPIV inhibition by compounds was measured by recording the liberation of free pNA at 405 nm. IC50 was determined from the slope of r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 81 total ) | Next | Last >>
Jump to: