Compile Data Set for Download or QSAR
maximum 50k data
Found 176 with Last Name = 'jarkas' and Initial = 'n'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)
Affinity DataKi:  0.0130nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139957(2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)ph...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50241199((Z)-2-[18F]fluoroethyl 3-(4-(2-iodovinyl)phenyl)-8...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189573(3-(4-iodo-phenyl)-5-methylene-7-aza-tricyclo[5.3.0...)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50200322(2beta-carbomethoxy-3beta-(3'-((Z)-2-iodoethenyl)ph...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]citalopram from human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50200323(2beta-carbomethoxy-3beta-(3'-((Z)-2-bromoethenyl)p...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]citalopram from human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)
Affinity DataKi:  0.25nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50247065(2beta-Carbo(2-fluoropropoxy)-3beta-(3'-((Z)-2-iodo...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189572(3-(4-bromo-phenyl)-5-methylene-7-aza-tricyclo[5.3....)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50230708(CHEMBL253184 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50160248((2S,3S)-2-[alpha-(2-Methylphenylthio)phenylmethyl]...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50230706(CHEMBL253387 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50247029(2beta-Carbo(2-fluoroethoxy)-3beta-(3'-((Z)-2-bromo...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50247066(2beta-Carbo(2-fluoropropoxy)-3beta-(3'-((Z)-2-bmor...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50247028(2beta-Carbo(2-fluoroethoxy)-3beta-(3'-((Z)-2-iodoe...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169004(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-ethyl-p...)
Affinity DataKi:  0.490nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465(CHEMBL190937 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi:  0.570nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465(CHEMBL190937 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50160246((2S,3S)-2-[alpha-(2-methoxyphenylthio)phenylmethyl...)
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189574(3-(4-chloro-phenyl)-5-methylene-7-aza-tricyclo[5.3...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]citalopram from human SERT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Institute For Degenerative Diseases

Curated by ChEMBL
LigandPNGBDBM50198230((S)-2-((S)-(2-iodophenoxy)(phenyl)methyl)morpholin...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]nisoxetine from NET in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50199005((S)-2-((S)-(2-methoxyphenoxy)(phenyl)methyl)morpho...)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50199005((S)-2-((S)-(2-methoxyphenoxy)(phenyl)methyl)morpho...)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50373031(CHEMBL411263)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254209((2S,3S)-2-[alpha-(2-Methylphenoxy)phenylmethyl]mor...)
Affinity DataKi:  1.02nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50370475(S,S-REBOXETINE)
Affinity DataKi:  1.04nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169010(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-vinyl-p...)
Affinity DataKi:  1.12nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50373028(CHEMBL411262)
Affinity DataKi:  1.21nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50230707(CHEMBL253182 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi:  1.26nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50373029(CHEMBL272002)
Affinity DataKi:  1.32nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50373030(CHEMBL270099)
Affinity DataKi:  1.35nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169009(2-(2-Dimethylaminomethyl-phenylsulfanyl)-phenylami...)
Affinity DataKi:  1.59nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210954((1R,2S,3R,5R)-methyl 3-(3-fluoro-4-methylphenyl)-8...)
Affinity DataKi:  1.78nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210953((1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bic...)
Affinity DataKi:  1.86nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210955((1R,2S,3R,5R)-methyl 3-(4-iodophenyl)-8-aza-bicycl...)
Affinity DataKi:  1.98nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169006(5-Ethyl-2-(2-methylaminomethyl-phenylsulfanyl)-phe...)
Affinity DataKi:  2.04nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50373032(CHEMBL272003)
Affinity DataKi:  2.06nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210955((1R,2S,3R,5R)-methyl 3-(4-iodophenyl)-8-aza-bicycl...)
Affinity DataKi:  2.25nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210953((1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bic...)
Affinity DataKi:  2.26nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Institute For Degenerative Diseases

Curated by ChEMBL
LigandPNGBDBM50198226(2-((2-iodophenoxy)(phenyl)methyl)morpholine | CHEM...)
Affinity DataKi:  2.47nMAssay Description:Displacement of [3H]nisoxetine from NET in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189572(3-(4-bromo-phenyl)-5-methylene-7-aza-tricyclo[5.3....)
Affinity DataKi:  2.94nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189571(CHEMBL383873 | [3-(4-bromo-phenyl)-7-aza-tricyclo[...)
Affinity DataKi:  2.94nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254210((2S,3S)-2-[alpha-(2-(2-Fluoroethyl)phenoxy)phenylm...)
Affinity DataKi:  3.14nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210953((1R,2S,3R,5R)-methyl 3-(4-ethynylphenyl)-8-aza-bic...)
Affinity DataKi:  3.45nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254211((2S,3S)-2-[alpha-(2-(3-Fluoropropyl)phenoxy)phenyl...)
Affinity DataKi:  3.68nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210955((1R,2S,3R,5R)-methyl 3-(4-iodophenyl)-8-aza-bicycl...)
Affinity DataKi:  4.16nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189569(CHEMBL215236 | [3-(4-chloro-phenyl)-7-aza-tricyclo...)
Affinity DataKi:  4.54nMAssay Description:Displacement of [125I]RTI-55 from human DAT transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210951((1R,2S,3R,5R)-methyl 3-(4-vinylphenyl)-8-aza-bicyc...)
Affinity DataKi:  4.67nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50189574(3-(4-chloro-phenyl)-5-methylene-7-aza-tricyclo[5.3...)
Affinity DataKi:  4.84nMAssay Description:Displacement of [3H]nisoxetine from human NET transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50210952((1R,2S,3R,5R)-methyl 3-p-tolyl-8-aza-bicyclo[3.2.1...)
Affinity DataKi:  4.88nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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