BindingDB PrimarySearch_ki

Found 676 with Last Name = 'jiang' and Initial = 'zy'

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM333146(Compound I | US10196404, Example 1 | US10196404, E...)

Ki: <1nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

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3D Structure (crystal)

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50519614(CHEMBL4439276)

Ki: <1.20nMAssay Description:Binding affinity to C-terminal MBP-fused human MCL1 (173 to 321 residues) expressed in Escherichia coli BL21(DE3)pLysS incubated for 2 hrs by fluores...More data for this Ligand-Target Pair

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3D Structure (crystal)

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50078163(CHEMBL3417704)

Ki: 6nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576654(CHEMBL4845828)

Ki: 18nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576622(CHEMBL4850731)

Ki: 20nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

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Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50092312(Birabresib | MK-8628 | OTX-015)

Ki: 27nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair

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3D Structure (crystal)

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576653(CHEMBL4848900)

Ki: 40nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576650(CHEMBL4865403)

Ki: 60nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576655(CHEMBL4848433)

Ki: 70nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576652(CHEMBL4872248)

Ki: 70nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591847(CHEMBL5194033)

Ki: 77nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) by a fluorescence anisotropy binding assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576639(CHEMBL4866213)

Ki: 80nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576631(CHEMBL4849603)

Ki: 120nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576659(CHEMBL4862358)

Ki: 130nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576658(CHEMBL4868509)

Ki: 140nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576651(CHEMBL4860413)

Ki: 150nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576647(CHEMBL4851153)

Ki: 150nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576628(CHEMBL4872240)

Ki: 170nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576656(CHEMBL4868575)

Ki: 170nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576663(CHEMBL4849319)

Ki: 180nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576643(CHEMBL4856732)

Ki: 190nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576649(CHEMBL4873637)

Ki: 200nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576661(CHEMBL4873329)

Ki: 200nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576634(CHEMBL4853919)

Ki: 240nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576662(CHEMBL4878600)

Ki: 260nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576666(CHEMBL4872295)

Ki: 340nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576657(CHEMBL4848776)

Ki: 340nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576640(CHEMBL4846014)

Ki: 360nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576660(CHEMBL4849994)

Ki: 380nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576664(CHEMBL4852847)

Ki: 420nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576665(CHEMBL4857430)

Ki: 420nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576645(CHEMBL4851400)

Ki: 430nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576625(CHEMBL4871992)

Ki: 470nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576644(CHEMBL4846741)

Ki: 500nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576648(CHEMBL4849257)

Ki: 550nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576635(CHEMBL4865519)

Ki: 680nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576624(CHEMBL4846109)

Ki: 700nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591847(CHEMBL5194033)

Ki: 718nMAssay Description:Binding affinity to BRD4 BD2 (unknown origin) by a fluorescence anisotropy binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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3D Structure (crystal)

Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591842(CHEMBL5169529)

Ki: 790nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576632(CHEMBL4859893)

Ki: 810nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591839(CHEMBL5207039)

Ki: 830nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591844(CHEMBL5199297)

Ki: 870nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576638(CHEMBL4858756)

Ki: 900nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591843(CHEMBL5181938)

Ki: 1.19E+3nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591840(CHEMBL5202265)

Ki: 1.25E+3nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591841(CHEMBL5206735)

Ki: 1.38E+3nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591846(CHEMBL5171707)

Ki: 1.48E+3nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Induced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50576633(CHEMBL4873135)

Ki: 1.60E+3nMAssay Description:Inhibition of FITC-labeled Bak BH3 peptide binding to GST-tagged MCL1 (171 to 327 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Details Article PubMed

Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591845(CHEMBL5201196)

Ki: 1.73E+3nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Bromodomain-containing protein 4(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50591837(CHEMBL5187309)

Ki: 1.74E+3nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using FAM-labeled JQ-1 as fluorescent substrate assessed as inhibition constant incubated for 30 mins by comp...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Displayed 1 to 50 (of 676 total ) | Next | Last >>

Filter my 676 hits

Targets 21▿
- Kelch-like ECH-associated protein 1 229
- Inhibitor of nuclear factor kappa-B kinase subunit beta 160
- Nuclear factor erythroid 2-related factor 2 104
- WD repeat-containing protein 5 53
- Induced myeloid leukemia cell differentiation protein Mcl-1 51
- Bromodomain-containing protein 4 29
- E3 ubiquitin-protein ligase CBL-B 23
- Heat shock protein HSP 90-alpha/90-beta 8
- Histone-lysine N-methyltransferase 2A/Retinoblastoma-binding protein 5/Set1/Ash2 histone methyltransferase complex subunit ASH2/WD repeat-containing protein 5 6
- 26S proteasome non-ATPase regulatory subunit 11 2
- Bcl-2-like protein 1 1
- Bcl-2-like protein 2 1
- Cytochrome P450 1A2 1
- Bcl-2-related protein A1 1
- Maltase-glucoamylase 1
- Cytochrome P450 2C9 1
- Cytochrome P450 2C19 1
- Cytochrome P450 2D6 1
- Apoptosis regulator Bcl-2 1
- Potassium voltage-gated channel subfamily H member 2 1
- Cytochrome P450 3A4 1
- ...
Publications 19▿
- Eur J Med Chem 63: 269-78 (2013) 160
- J Med Chem 63: 11149-11168 (2020) 107
- Eur J Med Chem 124: 480-489 (2016) 59
- J Med Chem 64: 11330-11353 (2021) 56
- J Med Chem 56: 7925-38 (2013) 43
- J Med Chem 62: 6796-6813 (2019) 41
- Eur J Med Chem 207: (2020) 32
- Eur J Med Chem 238: (2022) 29
- Bioorg Med Chem 38: (2021) 23
- J Med Chem 58: 6410-21 (2015) 22
- J Med Chem 59: 10837-10858 (2016) 20
- ACS Med Chem Lett 7: 835-40 (2016) 9
- Eur J Med Chem 143: 1578-1589 (2018) 7
- J Med Chem 57: 2736-45 (2014) 7
- Bioorg Med Chem 25: 233-240 (2017) 5
- Eur J Med Chem 136: 63-73 (2017) 3
- J Med Chem 65: 5029-5043 (2022) 2
- J Nat Prod 85: 405-414 (2022) 1
- J Med Chem 62: 3840-3856 (2019) 1
Institutions 2▿
- China Pharmaceutical University 626
- Yunnan University Of Chinese Medicine 1
Affinity: 0.14 to 1.0E+6 nM▿
- Ki 69
- IC50 473
- Kd 85
- EC50 49
- Affinity ≤ nM
Xtal structures: 12
Docked structures: 0
Catalog Cmpds: 42