TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Competitive inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by Lineweaver-Burk plot analysis in presence of...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of dCK (unknown origin) by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of dCK (unknown origin) by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of dCK (unknown origin) by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.5nMAssay Description:Inhibition of dCK (unknown origin) by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Inhibition of 5-HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Binding affinity to 5-HT2AMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
Affinity DataKi: 585nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 735nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.61E+3nMAssay Description:Apparent inhibition of human dCK by steady-state kinetic assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.100nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.200nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.200nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.200nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.200nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.308nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
Affinity DataIC50: 0.366nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
Affinity DataIC50: 0.366nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells by methyl-alpha-D-glucopyranoside assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.400nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Korea Research Institute of Chemical Technology
US Patent
Korea Research Institute of Chemical Technology
US Patent
Affinity DataIC50: 0.400nMAssay Description:The composition of the assay buffer used in the activity measurement was 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 7.5 mM MgCl2, 3 mM KCl, 0.01% Tween 20, ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.404nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair