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Found 45 with Last Name = 'junop' and Initial = 'ms'
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18049(3-({[(4-{[(carbamimidamidomethanimidoyl)sulfanyl]m...)
Affinity DataKi:  11.5nM ΔG°:  -45.3kJ/molepH: 7.5 T: 2°CAssay Description:The oxidation of NADPH was monitored at 340 nm using a Molecular Devices SpectraMax Plus 96-well microtiter plate reading spectrophotometer. Plots we...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  3nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18049(3-({[(4-{[(carbamimidamidomethanimidoyl)sulfanyl]m...)
Affinity DataIC50:  75nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18067(3-({[(3-{[(carbamimidamidomethanimidoyl)sulfanyl]m...)
Affinity DataIC50:  75nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370860(CHEMBL219268)
Affinity DataIC50:  79nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-beta-D-heptose 7-phosphate kinase(Burkholderia cepacia (strain J2315 / LMG 16656) (B...)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50425038(CHEMBL2312560)
Affinity DataIC50:  230nMAssay Description:Inhibition of Burkholderia cenocepacia HldA assessed as ATP depletion after 30 mins by luminescence assayMore data for this Ligand-Target Pair
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370870(CHEMBL218090)
Affinity DataIC50:  280nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370869(CHEMBL220764)
Affinity DataIC50:  530nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370861(CHEMBL221848)
Affinity DataIC50:  650nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-beta-D-heptose 7-phosphate kinase(Burkholderia cepacia (strain J2315 / LMG 16656) (B...)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50425039(CHEMBL2312559)
Affinity DataIC50:  810nMAssay Description:Inhibition of Burkholderia cenocepacia HldA assessed as ATP depletion after 30 mins by luminescence assayMore data for this Ligand-Target Pair
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370865(CHEMBL221706)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370853(CHEMBL221182)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370850(CHEMBL373750)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18055(3-({[(4-methoxyphenyl)methyl]sulfanyl}methanimidoy...)
Affinity DataIC50:  3.30E+3nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370867(CHEMBL221705)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18056(3-({[(3,4-dichlorophenyl)methyl]sulfanyl}methanimi...)
Affinity DataIC50:  3.70E+3nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18051(3-({[(3-methoxyphenyl)methyl]sulfanyl}methanimidoy...)
Affinity DataIC50:  3.80E+3nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18052(3-[({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)me...)
Affinity DataIC50:  4.30E+3nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370855(CHEMBL218737)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18064(3-[({[3,5-bis(trifluoromethyl)phenyl]methyl}sulfan...)
Affinity DataIC50:  5.60E+3nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370857(CHEMBL220531)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370854(CHEMBL220494)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370864(CHEMBL451558)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370856(CHEMBL376005)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18057(3-({[(4-methylphenyl)methyl]sulfanyl}methanimidoyl...)
Affinity DataIC50:  1.26E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18058(3-[({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)me...)
Affinity DataIC50:  1.30E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18059(3-({[(4-chlorophenyl)methyl]sulfanyl}methanimidoyl...)
Affinity DataIC50:  1.42E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370866(CHEMBL219582)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18062(3-({[(2-hydroxy-5-nitrophenyl)methyl]sulfanyl}meth...)
Affinity DataIC50:  1.51E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370848(CHEMBL218058)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18053(3-({[(3-nitrophenyl)methyl]sulfanyl}methanimidoyl)...)
Affinity DataIC50:  1.89E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18065(3-({[(2E)-3-phenylprop-2-en-1-yl]sulfanyl}methanim...)
Affinity DataIC50:  1.98E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18060(3-({[(4-fluorophenyl)methyl]sulfanyl}methanimidoyl...)
Affinity DataIC50:  2.49E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370858(CHEMBL220530)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370859(CHEMBL383877)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18054(3-[(benzylsulfanyl)methanimidoyl]guanidine | amidi...)
Affinity DataIC50:  3.46E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18066(3-({[(6-chloropyridin-3-yl)methyl]sulfanyl}methani...)
Affinity DataIC50:  3.47E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18061(3-({[(4-nitrophenyl)methyl]sulfanyl}methanimidoyl)...)
Affinity DataIC50:  3.51E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370852(CHEMBL219322)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Prince Edward Island

LigandPNGBDBM18063(3-[({[2-(trifluoromethyl)phenyl]methyl}sulfanyl)me...)
Affinity DataIC50:  4.06E+4nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370851(CHEMBL375564)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370863(CHEMBL222116)
Affinity DataIC50:  8.20E+4nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370868(CHEMBL218485)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370849(CHEMBL385118)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370862(CHEMBL221962)
Affinity DataIC50:  5.60E+5nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed