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Found 298 with Last Name = 'kachur' and Initial = 'jf'
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50405720(CHEMBL2115342)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228362(CHEMBL1202960)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228375(CHEMBL1202955)
Affinity DataKi:  195nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228357(CHEMBL1202954)
Affinity DataKi:  1.62E+3nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228377(CHEMBL1202958)
Affinity DataKi:  2.38E+3nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228354(CHEMBL557216)
Affinity DataKi:  3.98E+3nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228376(CHEMBL320755)
Affinity DataKi:  5.24E+3nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228355(CHEMBL1202956)
Affinity DataKi:  8.28E+3nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228356(CHEMBL1202957)
Affinity DataKi:  9.19E+3nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228353(CHEMBL1202959)
Affinity DataKi:  1.22E+4nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50228378(CHEMBL1202961)
Affinity DataKi:  1.26E+4nMAssay Description:Displacement of [3H]QNB from rat ileum Muscarinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50213060(CHEMBL355401 | SC-50135)
Affinity DataIC50: <0.100nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284125(7-[3-(4-Isopropylcarbamoyl-3-methoxy-2-propyl-phen...)
Affinity DataIC50:  0.100nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284122(7-[3-(4-Dimethylcarbamoyl-3-methoxy-2-propyl-pheno...)
Affinity DataIC50:  0.150nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116537(3-({3-[4-(Biphenyl-4-yloxy)-phenoxy]-propyl}-methy...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human whole blood LTB-4 production (Leukotriene B-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125433(1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-imidazo[4,5-b]py...)
Affinity DataIC50:  0.800nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284123(7-[3-(3-Methoxy-4-methylcarbamoyl-2-propyl-phenoxy...)
Affinity DataIC50:  0.850nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116563(CHEMBL323686 | N-(3-{[3-(4-Benzyl-phenoxy)-propyl]...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50001610(7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116554(CHEMBL119683 | N-(3-{[3-(4-Benzyl-phenoxy)-propyl]...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116562(CHEMBL117549 | [4-(4-Benzyl-phenoxy)-butylamino]-a...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116560(3-{Methyl-[3-(4-thiophen-3-ylmethyl-phenoxy)-propy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033746(7-[3-(4-Carbamoyl-3-methoxy-2-propyl-phenoxy)-prop...)
Affinity DataIC50:  2.40nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116538(3-{[3-(4-Benzyl-phenoxy)-propyl]-methyl-amino}-pro...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of leukotriene A4 hydrolase in human recombinant assayMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116538(3-{[3-(4-Benzyl-phenoxy)-propyl]-methyl-amino}-pro...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033743(7-[3-(2-Cyclopropylmethyl-3-methoxy-4-thiazol-4-yl...)
Affinity DataIC50:  3.20nMAssay Description:Binding affinity of the compound towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116544(2-{[3-(4-Benzyl-phenoxy)-propyl]-methyl-amino}-eth...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116542(3-{Methyl-[3-(4-thiophen-2-ylmethyl-phenoxy)-propy...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105264(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033744(7-{3-[3-Methoxy-2-propyl-4-(3H-[1,2,3]triazol-4-yl...)
Affinity DataIC50:  5.20nMAssay Description:Binding affinity of the compound towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284121(7-[3-(2-Cyclopropylmethyl-3-methoxy-4-methylcarbam...)
Affinity DataIC50:  5.30nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085261(CHEMBL163478 | [2-(4-Benzyl-phenoxy)-ethyl]-dimeth...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085288(1-{2-[4-(Biphenyl-4-yloxy)-phenoxy]-ethyl}-pyrroli...)
Affinity DataIC50:  6.60nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116548(3-{[3-(4-Benzyl-phenoxy)-propyl]-methyl-amino}-pro...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085282(5-Benzyl-2-(2-pyrrolidin-1-yl-ethoxy)-pyridine | C...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116561(3-[4-(4-Benzyl-phenoxy)-butylamino]-propionic acid...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125435(1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-imidazo[4,5-b]py...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284124(3-{(R)-7-[3-(2-Cyclopropylmethyl-3-methoxy-4-methy...)
Affinity DataIC50:  8.5nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085290(2-(4-Benzyl-phenoxy)-ethylamine | 2-(4-benzylpheno...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085277(1-{2-[4-(Difluoro-phenyl-methyl)-phenoxy]-ethyl}-p...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50052017(3-{7-[3-(2-Cyclopropylmethyl-3-methoxy-4-methylcar...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125420(5-[2-(4-Benzyl-phenoxy)-ethyl]-5H-imidazo[4,5-c]py...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033742(3-{7-[3-(2-Cyclopropylmethyl-3-methoxy-4-thiazol-4...)
Affinity DataIC50:  12.3nMAssay Description:Binding affinity of the compound towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116532(CHEMBL420502 | [4-(4-Benzyl-phenoxy)-butylamino]-a...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50121000(CHEMBL116174 | {2-[2-(4-Benzyl-phenoxy)-ethyl]-2-a...)
Affinity DataIC50:  15nMAssay Description:Inhibition of leukotriene A4 hydrolase in human recombinant assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50037390(3-{(S)-2-(2-Carboxy-ethyl)-7-[3-(2-cyclopropylmeth...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50121000(CHEMBL116174 | {2-[2-(4-Benzyl-phenoxy)-ethyl]-2-a...)
Affinity DataIC50:  15nMAssay Description:Inhibition of leukotriene A4 hydrolase in human recombinant assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033753(4-[3-(2-Cyclopropylmethyl-3-methoxy-4-thiazol-4-yl...)
Affinity DataIC50:  15.5nMAssay Description:Binding affinity of the compound towards Leukotriene B4 (LTB4) Receptor. Experiment conducted in the absence of NDGA.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50116529(3-{Methyl-[3-(4-thiophen-2-ylmethyl-phenoxy)-propy...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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