TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 102nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 174nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of rat muscle glycogen phosphorylase A assessed as release of inorganic phosphate from glucose-1- phosphate in presence of glycogen after ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 258nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of rat muscle glycogen phosphorylase A assessed as release of inorganic phosphate from glucose-1- phosphate in presence of glycogen after ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 281nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 306nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 397nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 416nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 455nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 461nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 589nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 709nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 825nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 862nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 1.49E+3nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of rat muscle glycogen phosphorylase A assessed as release of inorganic phosphate from glucose-1- phosphate in presence of glycogen after ...More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Griffith University
Curated by ChEMBL
Griffith University
Curated by ChEMBL
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetryMore data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Griffith University
Curated by ChEMBL
Griffith University
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetryMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 2.49E+3nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Griffith University
Curated by ChEMBL
Griffith University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetryMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 2.61E+3nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of rat muscle glycogen phosphorylase A assessed as release of inorganic phosphate from glucose-1- phosphate in presence of glycogen after ...More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Griffith University
Curated by ChEMBL
Griffith University
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetryMore data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Griffith University
Curated by ChEMBL
Griffith University
Curated by ChEMBL
Affinity DataIC50: 5.66E+3nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase-a assessed as formation of inorganic phosphate from glucose-1-phosphate by colorimetryMore data for this Ligand-Target Pair
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Griffith University
Curated by ChEMBL
Griffith University
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMpH: 7.2 T: 2°CAssay Description:RMGPa (Rabbit Muscle Glycogen Phosphorylase a) activity was measured in the direction of glycogen synthesis by the formation of inorganic phosphate f...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 6.73E+3nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 7.93E+3nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair