Compile Data Set for Download or QSAR
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Found 168 with Last Name = 'kasai' and Initial = 'm'
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity for estrogen receptor, by competition with [3H]estradiolMore data for this Ligand-Target Pair
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033123(CHEMBL3356618)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033119(CHEMBL3357062)
Affinity DataIC50:  3.90nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033101(CHEMBL2144205)
Affinity DataIC50:  4.60nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033108(CHEMBL3357064)
Affinity DataIC50:  8.60nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033107(CHEMBL3357065)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033124(CHEMBL3356617)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033102(CHEMBL3357070)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50296994(CHEMBL561939 | N-(5-Methanesulfonylamino-4,6-dimet...)
Affinity DataIC50:  13nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033126(CHEMBL3356616)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033132(CHEMBL3356615)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263150(CHEMBL513892 | N-(4,6-dimethyl-1-octylindolin-7-yl...)
Affinity DataIC50:  24nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033140(CHEMBL3356611)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297009(CHEMBL550526 | N-(1-decyl-4,6-dimethylindolin-7-yl...)
Affinity DataIC50:  27nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033103(CHEMBL3357069)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297008(CHEMBL558454 | N-(1-heptyl-4,6-dimethylindolin-7-y...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033135(CHEMBL3356614)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297017(CHEMBL555564 | N-[1-(Cyclobutylmethyl)-5-methanesu...)
Affinity DataIC50:  36nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297014(CHEMBL559117 | N-[5-Methanesulfonylamino-4,6-dimet...)
Affinity DataIC50:  40nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50296993(CHEMBL557522 | N-(1-Hexyl-5-methanesulfonylamino-4...)
Affinity DataIC50:  42nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50296992(CHEMBL559879 | N-(5-Methanesulfonylamino-4,6-dimet...)
Affinity DataIC50:  49nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297022(CHEMBL564138 | N-(1-Butyl-5-methanesulfonylamino-4...)
Affinity DataIC50:  53nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033105(CHEMBL3357067)
Affinity DataIC50:  56nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033106(CHEMBL3357066)
Affinity DataIC50:  56nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297010(CHEMBL561477 | N-(1-dodecyl-4,6-dimethylindolin-7-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297013(CHEMBL554505 | N-[1-(2,2-Dimethylpropyl)-5-methane...)
Affinity DataIC50:  61nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297007(CHEMBL561074 | N-(1-hexyl-4,6-dimethylindolin-7-yl...)
Affinity DataIC50:  67nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297015(CHEMBL559318 | N-[5-Methanesulfonylamino-4,6-dimet...)
Affinity DataIC50:  68nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50296991(CHEMBL551271 | N-(1-Butyl-5-methanesulfonylamino-4...)
Affinity DataIC50:  69nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297012(CHEMBL549649 | N-[5-Methanesulfonylamino-4,6-dimet...)
Affinity DataIC50:  71nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033118(CHEMBL3357063)
Affinity DataIC50:  73nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033120(CHEMBL3357061)
Affinity DataIC50:  73nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033122(CHEMBL3356619)
Affinity DataIC50:  84nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297018(CHEMBL556503 | N-[1-(Cyclopentyl)-5-methanesulfony...)
Affinity DataIC50:  95nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297006(CHEMBL563443 | N-(4,6-dimethyl-1-pentylindolin-7-y...)
Affinity DataIC50:  110nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033121(CHEMBL3357060)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033136(CHEMBL3356613)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297025(CHEMBL561135 | N-(5,7-dimethyl-6-(methylsulfonamid...)
Affinity DataIC50:  130nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297016(CHEMBL560997 | N-[1-(Cyclopropylmethyl)-5-methanes...)
Affinity DataIC50:  160nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033138(CHEMBL3356612)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 9(Homo sapiens (Human))
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50033164(CHEMBL3356610)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297005(CHEMBL538381 | N-(1-butyl-4,6-dimethylindolin-7-yl...)
Affinity DataIC50:  220nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50296990(CHEMBL559348 | N-(5-Methanesulfonylamino-4,6-dimet...)
Affinity DataIC50:  240nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297023(CHEMBL556232 | N-(1-Butyl-5-methanesulfonylamino-4...)
Affinity DataIC50:  240nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297019(CHEMBL551410 | N-[5-Methanesulfonylamino-1-(2-meth...)
Affinity DataIC50:  270nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263192(CHEMBL478858 | CHEMBL564483 | Pactimibe | [7-(2,2-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL after differentiation assessed as effect on...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297020(CHEMBL563918 | N-[1-(2-Ethoxyethyl)-5-methanesulfo...)
Affinity DataIC50:  310nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263196(CHEMBL478015 | N-(5-Aminomethyl-4,6-dimethyl-1-oct...)
Affinity DataIC50:  330nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50209683((R)-2-(4-(9-bromo-2,3-dimethylnaphtho[2,3-b]thioph...)
Affinity DataIC50:  410nMAssay Description:Inhibition of PTB1B using pNPP as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50297024(CHEMBL563699 | N-(1-Isobutyl-5-methanesulfonylamin...)
Affinity DataIC50:  480nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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