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Found 379 with Last Name = 'kasiewski' and Initial = 'c'
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080514(3-[(R)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataKi:  0.0470nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM14059(4-hydroxy-3-[[(3S)-2-oxo-3-(9-thia-5-azabicyclo[4....)
Affinity DataKi:  0.700nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123781(4-(4-Amino-quinazolin-7-ylmethyl)-1-(6-chloro-benz...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity (in vitro) of the compound towards human Coagulation factor X was determined at 10 mg/kg peroral doseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM12596(4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity (in vitro) of the compound towards human Coagulation factor X was determined at 5 mg/kg peroral doseMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081505(3-[(S)-3-(5-Chloro-thieno[3,2-b]pyridine-2-sulfony...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081512(3-[(S)-3-(4-Chloro-thieno[3,2-c]pyridine-2-sulfony...)
Affinity DataKi:  2nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081499(4-Hydroxy-3-[(S)-2-oxo-3-(thieno[2,3-c]pyridine-2-...)
Affinity DataKi:  2nMAssay Description:Binding affinity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081510(4-Amino-3-[(S)-3-(5-chloro-thieno[3,2-b]pyridine-2...)
Affinity DataKi:  3nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM12595(4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-1-{[1-(2-...)
Affinity DataKi:  3nMAssay Description:Binding affinity (in vitro) of the compound towards human Coagulation factor X was determined at 10 mg/kg peroral doseMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123788(4-(6-Bromo-benzo[b]thiophene-2-sulfonyl)-1-(1H-pyr...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081517(4-Hydroxy-3-[(S)-2-oxo-3-(thieno[3,2-c]pyridine-2-...)
Affinity DataKi:  3nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123766(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1-met...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM13286(4-Hydroxy-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfon...)
Affinity DataKi:  3nMAssay Description:Binding affinity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123782(4-(6-Chloro-thieno[2,3-b]pyridine-2-sulfonyl)-1-(1...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123767(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-py...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081515(4-Amino-3-[(S)-3-(5-methoxy-thieno[3,2-b]pyridine-...)
Affinity DataKi:  5nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081506(3-[(S)-3-(7-Chloro-thieno[2,3-c]pyridine-2-sulfony...)
Affinity DataKi:  5nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM13279(4-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfo...)
Affinity DataKi:  7nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123778(2-{2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-...)
Affinity DataKi:  8nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080482(4-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataKi:  11nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123765(CHEMBL158689 | {2-[4-(6-Chloro-benzo[b]thiophene-2...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080498(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-thiop...)
Affinity DataKi:  19nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080503(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-(1H-p...)
Affinity DataKi:  21nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM13282(3-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfo...)
Affinity DataKi:  22nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123789(4-(5'-Chloro-[2,2']bithiophenyl-5-sulfonyl)-1-(1H-...)
Affinity DataKi:  23nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080475(2-[[(S)-1-(3-Carbamimidoyl-benzyl)-2-oxo-pyrrolidi...)
Affinity DataKi:  25nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081011(3-[(S)-2-Oxo-3-(thieno[3,2-b]pyridine-2-sulfonylam...)
Affinity DataKi:  26nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080500(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-pyrid...)
Affinity DataKi:  31nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081520(3-[(S)-3-(5-Chloro-thieno[3,2-b]pyridine-2-sulfony...)
Affinity DataKi:  31nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080496(3-{(S)-3-[(7-Methoxy-naphthalene-2-sulfonyl)-thiop...)
Affinity DataKi:  34nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081513(3-[(S)-3-(5-Chloro-3-methyl-benzo[b]thiophene-2-su...)
Affinity DataKi:  36nMAssay Description:Binding affinity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123785(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(5-oxy...)
Affinity DataKi:  38nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081509(3-[(S)-3-(4-Chloro-thieno[3,2-c]pyridine-2-sulfony...)
Affinity DataKi:  39nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080501(3-{(S)-3-[Benzyl-(7-methoxy-naphthalene-2-sulfonyl...)
Affinity DataKi:  41nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080510(3-{(S)-3-[Ethyl-(7-methoxy-naphthalene-2-sulfonyl)...)
Affinity DataKi:  43nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123770(4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-(1H-py...)
Affinity DataKi:  45nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM13280(3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-...)
Affinity DataKi:  47nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM13280(3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-...)
Affinity DataKi:  47nMAssay Description:Binding affinity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50123775(4-[2-(4-Chloro-phenyl)-ethenesulfonyl]-1-(1H-pyrro...)
Affinity DataKi:  48nMAssay Description:In vitro binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080485(3-[[(S)-1-(3-Carbamimidoyl-benzyl)-2-oxo-pyrrolidi...)
Affinity DataKi:  56nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080487(3-[(S)-3-(6-Chloro-naphthalene-2-sulfonylamino)-2-...)
Affinity DataKi:  70nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080476(3-[(S)-3-(7-Chloro-naphthalene-2-sulfonylamino)-2-...)
Affinity DataKi:  78nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
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Curated by ChEMBL
LigandPNGBDBM50080479(CHEMBL117156 | N-(3-Carbamimidoyl-benzyl)-2-(napht...)
Affinity DataKi:  80nMAssay Description:Inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080492(5-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataKi:  83nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081507(3-[(S)-2-Oxo-3-(thieno[2,3-b]pyridine-2-sulfonylam...)
Affinity DataKi:  88nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50081522(3-[(S)-3-(1-Amino-isoquinoline-6-sulfonylamino)-2-...)
Affinity DataKi:  90nMAssay Description:Binding affinity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50080480(3-[(S)-3-(3'-Methoxy-biphenyl-4-sulfonylamino)-2-o...)
Affinity DataKi:  100nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50080506(3-[(S)-3-(7-Methyl-naphthalene-2-sulfonylamino)-2-...)
Affinity DataKi:  100nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50081518(3-[(S)-3-(2-Chloro-quinoline-6-sulfonylamino)-2-ox...)
Affinity DataKi:  110nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50080481(4-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...)
Affinity DataKi:  110nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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