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Found 38 with Last Name = 'kaur' and Initial = 't'
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16300(INH-NAD Adduct | ISONICOTINIC-ACETYL-NICOTINAMIDE-...)
Affinity DataKi:  0.75nM ΔG°:  -51.6kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16298(5-Octyl-2-phenoxy-phenol | 5-heptyl-2-phenoxylphen...)
Affinity DataKi:  1.10nM ΔG°:  -50.6kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16297(5-Hexyl-2-phenoxy-phenol | 5-hexyl-2-phenoxylpheno...)
Affinity DataKi:  9.40nM ΔG°:  -45.4kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16296(5-Pentyl-2-phenoxy-phenol | 5-pentyl-2-phenoxylphe...)
Affinity DataKi:  11.8nM ΔG°:  -44.8kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16299(14PP | 2-phenoxy-5-tetradecylphenol)
Affinity DataKi:  30.3nM ΔG°:  -42.5kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataKi:  220nM ΔG°:  -37.6kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16298(5-Octyl-2-phenoxy-phenol | 5-heptyl-2-phenoxylphen...)
Affinity DataIC50:  5nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16297(5-Hexyl-2-phenoxy-phenol | 5-hexyl-2-phenoxylpheno...)
Affinity DataIC50:  11nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16296(5-Pentyl-2-phenoxy-phenol | 5-pentyl-2-phenoxylphe...)
Affinity DataIC50:  17nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16295(4PP | 5-Butyl-2-phenoxy-phenol | 5-butyl-2-phenoxy...)
Affinity DataIC50:  80nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16299(14PP | 2-phenoxy-5-tetradecylphenol)
Affinity DataIC50:  150nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataIC50:  1.00E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16294(2PP | 5-Ethyl-2-phenoxy-phenol | 5-butyl-2-phenoxy...)
Affinity DataIC50:  2.00E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50348824(CHEMBL4177195)
Affinity DataIC50:  2.30E+3nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50348830(CHEMBL4169355)
Affinity DataIC50:  3.70E+3nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50342407(CHEMBL4174649)
Affinity DataIC50:  4.30E+3nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50346949(CHEMBL4163991)
Affinity DataIC50:  5.70E+3nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50342411(CHEMBL4170052)
Affinity DataIC50:  8.30E+3nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50342408(CHEMBL4162127)
Affinity DataIC50:  1.03E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50350508(CHEMBL4165508)
Affinity DataIC50:  1.08E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50345905(CHEMBL4167853)
Affinity DataIC50:  1.17E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50345479(CHEMBL4172292)
Affinity DataIC50:  1.39E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50345477(CHEMBL4171210)
Affinity DataIC50:  1.41E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50350836(CHEMBL4175708)
Affinity DataIC50:  1.62E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50342409(CHEMBL4161003)
Affinity DataIC50:  1.62E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50345903(CHEMBL4167436)
Affinity DataIC50:  1.67E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50345902(CHEMBL4176121)
Affinity DataIC50:  1.72E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50342410(CHEMBL4159534)
Affinity DataIC50:  1.75E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50241242(2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen...)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of Plasmodium falciparum FablMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50345475(CHEMBL4175704)
Affinity DataIC50:  2.73E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50350481(CHEMBL4168929)
Affinity DataIC50:  2.75E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50345901(CHEMBL4167849)
Affinity DataIC50:  2.83E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50346881(CHEMBL4160599)
Affinity DataIC50:  2.84E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50345904(CHEMBL2139421)
Affinity DataIC50:  2.88E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50345478(CHEMBL4164411)
Affinity DataIC50:  3.22E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein lin-28 homolog A(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50345476(CHEMBL4063466)
Affinity DataIC50:  6.25E+4nMAssay Description:Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50482368(CHEMBL1173016)
Affinity DataIC50:  6.52E+4nMAssay Description:Inhibition of Plasmodium falciparum FablMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50482369(CHEMBL1172170)
Affinity DataIC50:  5.87E+5nMAssay Description:Inhibition of Plasmodium falciparum FablMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed