Affinity DataKi: 5.24E+3nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 5.38E+3nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 7.89E+3nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 8.24E+3nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.45E+3nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human 5HT2B receptor expressed in cos-7 cells assessed as [3H]5-HT uptake after 120 minsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Nippon Suisan Kaisha
Curated by ChEMBL
Nippon Suisan Kaisha
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human platelet PDE5 assessed as [3H]cGMP to [3H]GMP conversion pretreated 15 mins before substrate addition measured after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptakeMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Nippon Suisan Kaisha
Curated by ChEMBL
Nippon Suisan Kaisha
Curated by ChEMBL
Affinity DataIC50: 8.71E+4nMAssay Description:Inhibition of human platelet PDE5 assessed as [3H]cGMP to [3H]GMP conversion pretreated 15 mins before substrate addition measured after 20 minsMore data for this Ligand-Target Pair