TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.410nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...More data for this Ligand-Target Pair
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 0.970nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 0.970nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.07nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.07nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
TargetProtein kinase C epsilon type(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]PDBu from recombinant human PKC-epsilon after 5 mins by scintillation counting analysis in presence of phosphatidylserineMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 2.22nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.45nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.45nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.66nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.66nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.96nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.96nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chlorideMore data for this Ligand-Target Pair
Affinity DataKi: 3.38nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.38nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Inhibition of human erythrocyte purine nucleoside phosphorylase (PNPase) in the presence of zinc chlorideMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Massachusetts College Of Pharmacy And Health Sciences
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair