Compile Data Set for Download or QSAR
maximum 50k data
Found 329 with Last Name = 'kelley' and Initial = 'ja'
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244449((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244449((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50017890(CHEMBL3289012)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50017890(CHEMBL3289012)
Affinity DataKi:  0.410nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244449((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50017892(CHEMBL3289014)
Affinity DataKi:  0.690nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50017891(CHEMBL3289013)
Affinity DataKi:  0.870nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50017892(CHEMBL3289014)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50017891(CHEMBL3289013)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50017889(CHEMBL3289011)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50017889(CHEMBL3289011)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244866(CHEMBL511820 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244416(CHEMBL527875 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...)
Affinity DataKi:  2.07nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244416(CHEMBL527875 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...)
Affinity DataKi:  2.07nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50017890(CHEMBL3289012)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]PDBu from recombinant human PKC-epsilon after 5 mins by scintillation counting analysis in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50245091(CHEMBL519398 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...)
Affinity DataKi:  2.22nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244865(CHEMBL471153 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244693(CHEMBL516638 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...)
Affinity DataKi:  2.45nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244693(CHEMBL516638 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...)
Affinity DataKi:  2.45nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244961(CHEMBL472520 | rac-(E/Z)-(4-heptylidene-2-(hydroxy...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244961(CHEMBL472520 | rac-(E/Z)-(4-heptylidene-2-(hydroxy...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244413(CHEMBL488498 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...)
Affinity DataKi:  2.66nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244413(CHEMBL488498 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...)
Affinity DataKi:  2.66nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244414(CHEMBL488500 | rac-(E)-{4-[(4-Chlorophenyl)methyle...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244414(CHEMBL488500 | rac-(E)-{4-[(4-Chlorophenyl)methyle...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244648(CHEMBL453598 | rac-(E)-(2-(Hydroxymethyl)-5-oxo-4-...)
Affinity DataKi:  2.96nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244648(CHEMBL453598 | rac-(E)-(2-(Hydroxymethyl)-5-oxo-4-...)
Affinity DataKi:  2.96nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50245049(CHEMBL488706 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244740(CHEMBL461372 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...)
Affinity DataKi:  3.38nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244740(CHEMBL461372 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...)
Affinity DataKi:  3.38nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244908(CHEMBL511301 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244908(CHEMBL511301 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244482((4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-te...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244915(CHEMBL472002 | rac-(E)-{2-(Hydroxymethyl)-4-[(3-ni...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244643(CHEMBL452307 | rac-(E)-(4-{[4-(Dimethylamino)pheny...)
Affinity DataKi:  4.68nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244863(CHEMBL472362 | rac-(E)-{4-[(4-Chloro-3-fluoropheny...)
Affinity DataKi:  4.89nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50204623(CHEMBL223747 | [2-(hydroxymethyl)-4-(methylethylid...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]PDBu from PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244914(CHEMBL472001 | rac-(E)-{2-(Hydroxymethyl)-4-[(3-ni...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244690(CHEMBL358095 | rac-(E)-{4-[(4-Fluorophenyl)methyle...)
Affinity DataKi:  5.53nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244690(CHEMBL358095 | rac-(E)-{4-[(4-Fluorophenyl)methyle...)
Affinity DataKi:  5.53nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50204626((2-(hydroxymethyl)-5-oxo-4-(propan-2-ylidene)-tetr...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]PDBu from PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50017891(CHEMBL3289013)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]PDBu from recombinant human PKC-alpha after 5 mins by scintillation counting analysis in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244554(CHEMBL508402 | rac-(E)-{4-[(4-Chloro-3-fluoropheny...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244909(CHEMBL471137 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244909(CHEMBL471137 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244867(CHEMBL472171 | rac-(E)-{2-(Hydroxymethyl)-4-[(3-ni...)
Affinity DataKi:  8nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50017891(CHEMBL3289013)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]PDBu from recombinant human PKC-epsilon after 5 mins by scintillation counting analysis in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50017890(CHEMBL3289012)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]PDBu from recombinant human PKC-alpha after 5 mins by scintillation counting analysis in presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244861(CHEMBL512019 | rac-(E/Z)-(4-(4-bromobenzylidene)-2...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology

Curated by ChEMBL
LigandPNGBDBM50244971(CHEMBL471317 | rac-(E)-{2-(Hydroxymethyl)-4-[(2-ni...)
Affinity DataKi:  9.40nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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