TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Competitive inhibition of PTP1B mediated pNPP hydrolysis by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute
Curated by ChEMBL
Korea Basic Science Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute
Curated by ChEMBL
Korea Basic Science Institute
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of ascorbic acid/methylene blue activated recombinant human IDO expressed in Escherichia coli using L-Tryptophan as substrate after 60 min...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of ascorbic acid/methylene blue activated recombinant human IDO expressed in Escherichia coli using L-Tryptophan as substrate after 60 min...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of ascorbic acid/methylene blue activated recombinant human IDO expressed in Escherichia coli using L-Tryptophan as substrate after 60 min...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute
Curated by ChEMBL
Korea Basic Science Institute
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute
Curated by ChEMBL
Korea Basic Science Institute
Curated by ChEMBL
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute
Curated by ChEMBL
Korea Basic Science Institute
Curated by ChEMBL
Affinity DataIC50: 4.75E+3nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute
Curated by ChEMBL
Korea Basic Science Institute
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of PLCgamma1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute
Curated by ChEMBL
Korea Basic Science Institute
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of HA-EGFP tagged Plk1 polo-box domain (unknown origin) expressed in 293A cells assessed as inhibition of biotin-p-T78 binding after 1 hr ...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology (Kribb)
Curated by ChEMBL
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of VHR DS-PTPMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of PLCgamma1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Korea Basic Science Institute
Curated by ChEMBL
Korea Basic Science Institute
Curated by ChEMBL
Affinity DataIC50: 1.64E+4nMAssay Description:Displacement of 5-carboxyfluorescein-labeled PBD-binding peptide from PLk1 PBD (unknown origin) expressed in bacterial expression system incubated fo...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of PTP1B mediated pNPP hydrolysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PLCgamma1 (unknown origin)More data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University
Curated by ChEMBL
Silla University
Curated by ChEMBL
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair