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Found 464 with Last Name = 'kim' and Initial = 'hk'
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50246899((S)-2-(3-((S)-1-carboxy-5-(4-iodobenzamido)pentyl)...)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of PSMA (unknown origin)More data for this Ligand-Target Pair
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50454862(CHEMBL4211875)
Affinity DataKi:  0.140nMAssay Description:Inhibition of PSMA in human LNCaP cell lysates incubated for 2 hrs in presence of N-acetylaspartylglutamate by Amplex red glutamic acid/glutamate oxi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50454861(CHEMBL4206989)
Affinity DataKi:  0.380nMAssay Description:Inhibition of PSMA in human LNCaP cell lysates incubated for 2 hrs in presence of N-acetylaspartylglutamate by Amplex red glutamic acid/glutamate oxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50454860(CHEMBL4202635)
Affinity DataKi:  0.580nMAssay Description:Inhibition of PSMA in human LNCaP cell lysates incubated for 2 hrs in presence of N-acetylaspartylglutamate by Amplex red glutamic acid/glutamate oxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50428286(DABRAFENIB | GSK2118436A)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of fluoromone binding to recombinant human full length untagged ERbeta expressed in insect cells after 2 hrs by fluorescence polarization ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133707(US8846699, 23)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133696(US8846699, 12)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133709(US8846699, 25)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133702(US8846699, 18)
Affinity DataIC50:  2nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563431(CHEMBL4793723)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133701(US8846699, 17)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133685(US8846699, 1)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133689(US8846699, 5)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133711(US8846699, 27 | US8846699, 55)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563437(Arry-614 | Pexmetinib)
Affinity DataIC50:  4nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM221688(US10568884, Cpd 9 | US9314464, 9 | US9593100, Comp...)
Affinity DataIC50:  4nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133819(US8846699, 137)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133697(US8846699, 13)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133708(US8846699, 24)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133713(US8846699, 29)
Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563432(CHEMBL4797100)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of fluoromone binding to recombinant human full length untagged ERalpha expressed in insect cells after 2 hrs by fluorescence polarization...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133803(US8846699, 121)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133710(US8846699, 26)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133706(US8846699, 22)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563427(CHEMBL4758203)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133694(US8846699, 10)
Affinity DataIC50:  6nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133826(US8846699, 144)
Affinity DataIC50:  7nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133783(US8846699, 101)
Affinity DataIC50:  7nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50173609(CHEMBL363648 | D3RKN_11 | N-[4-(2-Ethyl-4-m-tolyl-...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563436(CHEMBL4741154)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563435(CHEMBL4763666)
Affinity DataIC50:  8nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133848(US8846699, 168)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133705(US8846699, 21)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50563430(CHEMBL4779919)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133745(US8846699, 61)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133703(US8846699, 19)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133822(US8846699, 140)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133817(US8846699, 135)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133704(US8846699, 20)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133700(US8846699, 16)
Affinity DataIC50:  11nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133829(US8846699, 147)
Affinity DataIC50:  12nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133801(US8846699, 119)
Affinity DataIC50:  12nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133793(US8846699, 111)
Affinity DataIC50:  12nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133784(US8846699, 102)
Affinity DataIC50:  12nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133838(US8846699, 158 | US8846699, 163)
Affinity DataIC50:  12nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133692(US8846699, 8)
Affinity DataIC50:  13nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133778(US8846699, 96)
Affinity DataIC50:  13nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM133816(US8846699, 134)
Affinity DataIC50:  13nMpH: 7.4 T: 2°CAssay Description:EGFR1 (HER-1) enzyme assay was carried out by using Tyrosine Kinase Assay Kit Green. The entire assay was conducted in accordance with EGFR PTK inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent
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