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Found 283 with Last Name = 'kim' and Initial = 'jm'
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50052442((4-Hydroxy-3-methoxy-phenyl)-acetic acid (2R,3S,3a...)
Affinity DataKi:  0.130nMAssay Description:In vitro binding to Rat Vanilloid receptor 1 (VR1) expressing CHO cells compared to capsacinMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50196343(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)
Affinity DataKi:  6.35nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20293(2-[(3,4-dimethylphenyl)methyl]-3-({[(3-fluoro-4-me...)
Affinity DataKi:  7.80nMAssay Description:Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50196337(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  17.4nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130546(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)
Affinity DataKi:  25.2nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130542(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  29.3nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130548(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  49nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20293(2-[(3,4-dimethylphenyl)methyl]-3-({[(3-fluoro-4-me...)
Affinity DataKi:  54nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130540(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)
Affinity DataKi:  64nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130542(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  67nMAssay Description:Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130544(Benzoic acid 2-(4-tert-butyl-benzyl)-3-[3-(4-metha...)
Affinity DataKi:  77.2nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130540(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)
Affinity DataKi:  86nMAssay Description:Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130553(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  108nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130552(Benzoic acid 2-(3,4-dimethyl-benzyl)-3-[3-(4-metha...)
Affinity DataKi:  148nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130539(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  227nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130545(Benzoic acid 2-(4-tert-butyl-benzyl)-3-[3-(4-metha...)
Affinity DataKi:  239nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130553(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  309nMAssay Description:Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130543(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  313nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130555(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  355nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130556(Benzoic acid 2-(3,4-dimethyl-benzyl)-3-[3-(4-metha...)
Affinity DataKi:  410nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20284(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)
Affinity DataKi:  520nMAssay Description:Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cellsMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataKi:  567nMAssay Description:Inhibition of mushroom tyrosinase at 1.25 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50339940(4-(Benzo[d]thiazol-2-yl)benzene-1,3-diol | CHEMBL1...)
Affinity DataKi:  673nMAssay Description:Inhibition of mushroom tyrosinase at 1.25 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130543(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  940nMAssay Description:Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20284(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)
Affinity DataKi:  1.30E+3nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of mushroom tyrosinase at 20 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130538(2,2-Dimethyl-propionic acid 3-[3-(4-acetylamino-be...)
Affinity DataKi:  1.70E+3nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20461((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)
Affinity DataKi:  1.70E+3nMAssay Description:In vitro binding to Rat Vanilloid receptor 1 (VR1) expressing CHO cells compared to capsacinMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20461((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)
Affinity DataKi:  1.80E+3nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130550(2,2-Dimethyl-propionic acid 3-[3-(4-benzenesulfony...)
Affinity DataKi:  2.50E+3nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130554(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  2.60E+3nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130551(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  3.00E+3nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50339940(4-(Benzo[d]thiazol-2-yl)benzene-1,3-diol | CHEMBL1...)
Affinity DataKi:  7.70E+3nMAssay Description:Inhibition of mushroom tyrosinase at 20 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458086(US10752604, Example 13)
Affinity DataIC50:  1.20nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458080(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50:  1.30nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458096(US10752604, Example 62)
Affinity DataIC50:  1.46nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458092(US10752604, Example 53)
Affinity DataIC50:  1.83nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458095(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50:  2.04nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin G(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349174(CHEMBL1807526)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458090(US10752604, Example 42)
Affinity DataIC50:  2.73nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458083(US10752604, Example 5)
Affinity DataIC50:  2.80nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458081(US10752604, Example 2)
Affinity DataIC50:  3nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458089(Preparation of (2S,3R,4R,5S,6R)-2-(4-ethyl-7-(4-me...)
Affinity DataIC50:  3.68nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473585(US10844062, Example 21)
Affinity DataIC50:  4.10nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin G(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349176(CHEMBL1807531)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM50386885(CANAGLIFLOZIN | CANAGLIFLOZIN HYDRATE | US10752604...)
Affinity DataIC50:  4.90nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458093(US10752604, Example 57)
Affinity DataIC50:  5.86nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Chlorocebus sabaeus (Green monkey) (Cercopithecus ...)
Dong-A St

US Patent
LigandPNGBDBM354702(Preparation of t-butyl(4-hydroxybenzyl)carbamate |...)
Affinity DataIC50:  6.30nMAssay Description:In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin G(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50349173(CHEMBL1807638)
Affinity DataIC50:  7nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Chlorocebus sabaeus (Green monkey) (Cercopithecus ...)
Dong-A St

US Patent
LigandPNGBDBM354706(Preparation of 4-((2R,5S)-5-((4-cyanophenoxy)methy...)
Affinity DataIC50:  7.60nMAssay Description:In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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