Affinity DataKi: 0.100nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.113nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
Affinity DataKi: 0.151nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
Affinity DataKi: 0.162nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
Affinity DataKi: 0.172nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
Affinity DataKi: 0.452nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibitory activity against HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibitory activity against HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.32E+3nMAssay Description:Inhibitory activity against HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+5nMAssay Description:Inhibitory activity against HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibitory activity against HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+7nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of MEK1 phosphorylation in LoVo cellsMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of c-Met (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration of the compound against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against Dual specificity mitogen-activated protein kinase kinase using coupled MEK assay (which uses activated Raf to activate an...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration of the compound against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration of the compound against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration of the compound against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration of the compound against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration of the compound against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibitory activity against Dual specificity mitogen-activated protein kinase kinase using coupled MEK assay (which uses activated Raf to activate an...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration of the compound against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of c-Met (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibitory activity against Dual specificity mitogen-activated protein kinase kinase using coupled MEK assay (which uses activated Raf to activate an...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sungkyunkwan University
Curated by ChEMBL
Sungkyunkwan University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Met (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration of the compound against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration of the compound against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair