Affinity DataIC50: 2.19E+3nMAssay Description:Antagonist activity at TLR8 in human HEK-SEAP reporter cell assessed as inhibition of methyl 4-amino-1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5...More data for this Ligand-Target Pair
Affinity DataIC50: 3.91E+3nMAssay Description:Antagonist activity at TLR7 in human HEK-SEAP reporter cell assessed as inhibition of methyl 4-amino-1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at TLR7 in human HEK-SEAP reporter cell assessed as inhibition of methyl 4-amino-1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5...More data for this Ligand-Target Pair
Affinity DataIC50: 4.41E+3nMAssay Description:Antagonist activity at TLR8 in human HEK-SEAP reporter cell assessed as inhibition of methyl 4-amino-1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5...More data for this Ligand-Target Pair
Affinity DataEC50: 1.90E+5nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.67E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.44E+4nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).More data for this Ligand-Target Pair
Affinity DataEC50: 1.14E+4nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.21E+3nMAssay Description:Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).More data for this Ligand-Target Pair
Affinity DataEC50: 3.85E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.67E+4nMAssay Description:Agonist activity at human TLR8 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+4nMAssay Description:Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).More data for this Ligand-Target Pair
Affinity DataEC50: 2.09E+4nMAssay Description:Agonist activity at human TLR8 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.13E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).More data for this Ligand-Target Pair
Affinity DataEC50: 1.74E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.33E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.84E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.21E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.72E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.06E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.22E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 9.88E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.89E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.34E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.89E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.92E+4nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.32E+4nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 3.68E+3nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 990nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 210nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at TLR7 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.88E+4nMAssay Description:Agonist activity at TLR8 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+4nMAssay Description:Agonist activity at TLR8 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.84E+3nMAssay Description:Agonist activity at TLR8 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Agonist activity at TLR8 in human HEK-SEAP reporter cell assessed as NF-kappaB activationMore data for this Ligand-Target Pair
Affinity DataEC50: 4.98E+4nMAssay Description:Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).More data for this Ligand-Target Pair
Affinity DataEC50: 5.34E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.64E+3nMAssay Description:Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).More data for this Ligand-Target Pair
Affinity DataEC50: 4.53E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.69E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assayMore data for this Ligand-Target Pair