Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.2kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -46.9kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 9nM ΔG°: -45.5kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 10nM ΔG°: -45.2kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -45.0kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -45.0kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataKi: 17nM ΔG°: -43.9kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
Affinity DataKi: 22nM ΔG°: -43.3kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 25nM ΔG°: -43.0kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
Affinity DataKi: 29nM ΔG°: -42.6kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 57nM ΔG°: -40.9kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 66nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 69nMAssay Description:In vitro inhibitory activity against glucagon induced monkey adenylate cyclaseMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
Affinity DataKi: 112nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 144nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 250nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 254nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
Affinity DataKi: 260nM ΔG°: -37.2kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
Affinity DataKi: 300nM ΔG°: -36.9kJ/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair