BindingDB PrimarySearch_ki

Found 189 with Last Name = 'lainchbury' and Initial = 'md'

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)

Ki: 0.100nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

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CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)

Ki: 0.100nMAssay Description:Inhibition of wild-type EGFR (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank
MMDB
PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)

Ki: 0.300nMAssay Description:Inhibition of EGFR T790M/del746 to 750 mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613695(CHEMBL5274166)

Ki: 0.350nMAssay Description:Inhibition of human EGFR T790M/del (746 to 750 residues) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as subs...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613687(CHEMBL5285503)

Ki: <0.600nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613688(CHEMBL5282716)

Ki: <0.600nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613684(CHEMBL5280555)

Ki: 0.790nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613698(CHEMBL5282384)

Ki: 1.10nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613695(CHEMBL5274166)

Ki: 1.10nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613695(CHEMBL5274166)

Ki: 1.20nMAssay Description:Inhibition of human EGFR del (746 to 750) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613686(CHEMBL5276357)

Ki: 1.20nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613699(CHEMBL5279275)

Ki: 1.20nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613699(CHEMBL5279275)

Ki: 1.40nMAssay Description:Inhibition of human EGFR del (746 to 750) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613699(CHEMBL5279275)

Ki: 1.60nMAssay Description:Inhibition of human EGFR T790M/del (746 to 750 residues) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as subs...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613693(CHEMBL5281373)

Ki: 1.80nMAssay Description:Inhibition of human EGFR T790M/del (746 to 750 residues) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as subs...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613687(CHEMBL5285503)

Ki: 2nMAssay Description:Inhibition of wild type human EGFR assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613698(CHEMBL5282384)

Ki: 2nMAssay Description:Inhibition of human EGFR del (746 to 750) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613698(CHEMBL5282384)

Ki: 2nMAssay Description:Inhibition of human EGFR T790M/del (746 to 750 residues) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as subs...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613685(CHEMBL5273791)

Ki: 2.10nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613699(CHEMBL5279275)

Ki: 3.40nMAssay Description:Inhibition of wild type human EGFR assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613692(CHEMBL5277269)

Ki: 3.5nMAssay Description:Inhibition of human EGFR T790M/del (746 to 750 residues) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as subs...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50498976(CHEMBL3736183)

Ki: 3.60nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Details PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613699(CHEMBL5279275)

Ki: 3.80nMAssay Description:Inhibition of human EGFR L858R mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as substrate preincubated for 30 ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613693(CHEMBL5281373)

Ki: 4.10nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613695(CHEMBL5274166)

Ki: 4.10nMAssay Description:Inhibition of human EGFR L858R mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as substrate preincubated for 30 ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613698(CHEMBL5282384)

Ki: 4.60nMAssay Description:Inhibition of wild type human EGFR assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613696(CHEMBL5282852)

Ki: 5.30nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613686(CHEMBL5276357)

Ki: 5.5nMAssay Description:Inhibition of wild type human EGFR assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613698(CHEMBL5282384)

Ki: 6.40nMAssay Description:Inhibition of human EGFR L858R mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as substrate preincubated for 30 ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613688(CHEMBL5282716)

Ki: 7nMAssay Description:Inhibition of wild type human EGFR assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613695(CHEMBL5274166)

Ki: 7.80nMAssay Description:Inhibition of wild type human EGFR assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613684(CHEMBL5280555)

Ki: 8.20nMAssay Description:Inhibition of wild type human EGFR assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032623(CHEMBL3354183)

Ki: 9nMAssay Description:Inhibition of EGFR T790M/del746 to 750 mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613685(CHEMBL5273791)

Ki: 10nMAssay Description:Inhibition of wild type human EGFR assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032630(CHEMBL3354191)

Ki: 12nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613693(CHEMBL5281373)

Ki: 12nMAssay Description:Inhibition of human EGFR del (746 to 750) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50499002(CHEMBL3735958)

Ki: 13nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032612(CHEMBL3352835)

Ki: 14nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032625(CHEMBL3354187)

Ki: 16nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032612(CHEMBL3352835)

Ki: 16nMAssay Description:Inhibition of Tyk2 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032627(CHEMBL3354189)

Ki: 17nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032631(CHEMBL3354192)

Ki: 18nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613692(CHEMBL5277269)

Ki: 18nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032627(CHEMBL3354189)

Ki: 20nMAssay Description:Inhibition of EGFR T790M/del746 to 750 mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032623(CHEMBL3354183)

Ki: 22nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613689(CHEMBL5281446)

Ki: 24nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613696(CHEMBL5282852)

Ki: 27nMAssay Description:Inhibition of human EGFR T790M/del (746 to 750 residues) mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 peptide as subs...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032620(CHEMBL3354184)

Ki: 28nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50613697(CHEMBL5268573)

Ki: 29nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant assessed as apparent inhibition constant using Fl-EEPLYWSFPAKKK-CONH2 as peptide substrate preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Epidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL

PNG

BDBM50032612(CHEMBL3352835)

Ki: 32nMAssay Description:Inhibition of EGFR T790M/del746 to 750 mutant (unknown origin) by high-throughput biochemical screeningMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

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