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Found 3578 with Last Name = 'lamb' and Initial = 'j'
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142111(1-{4'-[4-Chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)...)
Affinity DataKi:  0.0120nMAssay Description:Inhibitory concentration against coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193861(5-chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N,N-dimet...)
Affinity DataKi:  0.0440nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249120(CHEMBL472967 | N-(4-chloro-2-(5-chloropyridin-2-yl...)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50382290(CARIPRAZINE HYDROCHLORIDE | RGH-188 HCL)
Affinity DataKi:  0.0900nMAssay Description:Binding affinity to human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142112(2'-Dimethylamino-biphenyl-4-carboxylic acid [4-chl...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142125(2'-(Acetimidoylamino-methyl)-biphenyl-4-carboxylic...)
Affinity DataKi:  0.100nMAssay Description:Inhibitory concentration against coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142139(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-{4-[(N-methyl...)
Affinity DataKi:  0.100nMAssay Description:In vitro inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142090(2'-(N,N-Dimethyl-carbamimidoyl)-biphenyl-4-carboxy...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249423(CHEMBL515919 | N-(2-(5-chloropyridin-2-ylcarbamoyl...)
Affinity DataKi:  0.105nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249298(BEVYXXA | CHEMBL512351 | N-(5-chloropyridin-2-yl)-...)
Affinity DataKi:  0.117nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142118(2'-Amino-biphenyl-4-carboxylic acid [4-chloro-2-(5...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142169(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N,N'-dime...)
Affinity DataKi:  0.200nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142129(2'-(4-Hydroxy-piperidin-1-yl)-biphenyl-4-carboxyli...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142161(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-{[methyl-(...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142126(2'-Guanidinomethyl-biphenyl-4-carboxylic acid [4-c...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory concentration against coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142142(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N',N'-dim...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM7840(RIVAROXABAN | US8822458, 44 | US8822458, 97)
Affinity DataKi:  0.400nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50382312(CHEMBL2024677)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142158(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-i...)
Affinity DataKi:  0.5nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142177(2-{4-[(Acetimidoyl-methyl-amino)-methyl]-benzoylam...)
Affinity DataKi:  0.600nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A-interacting protein(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50382310(CHEMBL2024675)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140443(1-(6-Chloro-naphthalen-2-yl)-1H-tetrazole-5-carbox...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140413(2-(3-Fluoro-naphthalen-2-yl)-5-trifluoromethyl-2H-...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142089(3'-Carbamimidoyl-biphenyl-4-carboxylic acid [4-chl...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140424(2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...)
Affinity DataKi:  0.700nMAssay Description:In vitro inhibitory activity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142100(2'-(4-Methyl-[1,4]diazepan-1-yl)-biphenyl-4-carbox...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50382290(CARIPRAZINE HYDROCHLORIDE | RGH-188 HCL)
Affinity DataKi:  0.810nMAssay Description:Binding affinity to human dopamine D2S receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142103(2'-(4-Methyl-piperazin-1-yl)-biphenyl-4-carboxylic...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140410(2-(6-Chloro-naphthalen-2-yl)-5-trifluoromethyl-2H-...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142106(2'-Piperazin-1-yl-biphenyl-4-carboxylic acid [4-ch...)
Affinity DataKi:  1nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140422(2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...)
Affinity DataKi:  1nMAssay Description:Binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142154(CHEMBL174499 | {4-[4-Chloro-2-(5-chloro-pyridin-2-...)
Affinity DataKi:  1nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142096(3'-(N,N-Dimethyl-carbamimidoyl)-biphenyl-4-carboxy...)
Affinity DataKi:  1nMAssay Description:Inhibitory concentration against coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140415(2-(6-Chloro-naphthalen-2-yl)-5-trifluoromethyl-2H-...)
Affinity DataKi:  1.20nMAssay Description:In vitro inhibitory activity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142146(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-dimethylam...)
Affinity DataKi:  1.30nMAssay Description:In vitro inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249295(CHEMBL471725 | N-(5-chloropyridin-2-yl)-2-(4-(N,N-...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142163(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-o...)
Affinity DataKi:  1.5nMAssay Description:In vitro inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50382306(CHEMBL2024522)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142091(3'-(Acetimidoylamino-methyl)-biphenyl-4-carboxylic...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142094(2'-[1,4]Diazepan-1-yl-biphenyl-4-carboxylic acid [...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144092(CHEMBL294121 | [4-(5-Chloro-1H-indole-2-sulfonyl)-...)
Affinity DataKi:  1.90nMAssay Description:In vitro inhibitory activity of the compound against Coagulation factor X was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140418(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50382311(CHEMBL2024676)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323373(1,2-dicyclohexyl-3-(pyridin-3-yl)propan-1-one O-3-...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140409(2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140407(2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140417(2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity for human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of Aurora CMore data for this Ligand-Target Pair
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