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Found 245 with Last Name = 'leahy' and Initial = 'jj'
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataKi:  0.650nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataKi:  120nMAssay Description:Binding affinity for DNA dependent protein kinase isolated from HeLa cells; Range is 20-120More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)
Affinity DataKi:  120nMAssay Description:Inhibition of human recombinant p110 alpha Phosphatidylinositol 3-kinaseMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity for Phosphatidylinositol-3-kinase isolated from HeLa cells; Range is 20-120More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK)More data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178029(2-morpholin-4-yl-8-(6,7,8,9-tetrahydro-dibenzothio...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156503(8-Dibenzofuran-4-yl-2-morpholin-4-yl-chromen-4-one...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156503(8-Dibenzofuran-4-yl-2-morpholin-4-yl-chromen-4-one...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156498(2-(2-Methyl-morpholin-4-yl)-benzo[h]chromen-4-one ...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156498(2-(2-Methyl-morpholin-4-yl)-benzo[h]chromen-4-one ...)
Affinity DataIC50:  190nMAssay Description:Inhibition of DNA dependent protein kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50098126(2-(morpholin-4-yl)-benzo[h]chromen-4-one | 2-Morph...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50098126(2-(morpholin-4-yl)-benzo[h]chromen-4-one | 2-Morph...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50098126(2-(morpholin-4-yl)-benzo[h]chromen-4-one | 2-Morph...)
Affinity DataIC50:  230nMAssay Description:Inhibition of DNA dependent protein kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178120(2-morpholinobenzo[h]quinolin-4(1H)-one | CHEMBL198...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50159677(2-Morpholin-4-yl-benzo[h]chromene-4-thione | CHEMB...)
Affinity DataIC50:  260nMAssay Description:Inhibition of DNA dependent protein kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50159620(2-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-one ...)
Affinity DataIC50:  280nMAssay Description:Inhibition of DNA dependent protein kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156502(2-Morpholin-4-yl-8-thiophen-3-yl-chromen-4-one | 2...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156502(2-Morpholin-4-yl-8-thiophen-3-yl-chromen-4-one | 2...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178038(CHEMBL198482 | N-[3-(2-(morpholin-4-yl)-4-oxo-4H-c...)
Affinity DataIC50:  350nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50159621(2-Morpholin-4-yl-7,8,9,10-tetrahydro-benzo[h]chrom...)
Affinity DataIC50:  360nMAssay Description:Inhibition of DNA dependent protein kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178028(7-(benzyloxy)-2-morpholino-4H-chromen-4-one | 7-Be...)
Affinity DataIC50:  380nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50159668(2-Morpholin-4-yl-benzo[g]chromen-4-one | 2-morphol...)
Affinity DataIC50:  390nMAssay Description:Inhibition of DNA dependent protein kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50159668(2-Morpholin-4-yl-benzo[g]chromen-4-one | 2-morphol...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178033(7-(4-fluorobenzyloxy)-2-morpholin-4-yl-chromen-4-o...)
Affinity DataIC50:  440nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178080(7-(naphthalen-2-ylmethoxy)-2-(morpholin-4-yl)-chro...)
Affinity DataIC50:  440nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178123(7-hydroxy-2-(morpholin-4-yl)chromen-4-one | CHEMBL...)
Affinity DataIC50:  450nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178111(2-(2-(benzenesulfonyl)ethoxy)-2-morpholin-4-yl-chr...)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178126(7-(3-chlorobenzyloxy)-2-morpholin-4-yl-chromen-4-o...)
Affinity DataIC50:  490nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178118(7-(4-chlorobenzyloxy)-2-(morpholin-4-yl)-chromen-4...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156500(8-(4-Hydroxymethyl-phenyl)-2-morpholin-4-yl-chrome...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156500(8-(4-Hydroxymethyl-phenyl)-2-morpholin-4-yl-chrome...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178067(7-(4-cyanobenzyloxy)-2-morpholin-4-yl-chromen-4-on...)
Affinity DataIC50:  690nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156496(2-Morpholin-4-yl-8-thiophen-2-yl-chromen-4-one | 2...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156496(2-Morpholin-4-yl-8-thiophen-2-yl-chromen-4-one | 2...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178034(7-(4-methylsulfanylbenzyloxy)-2-(morpholin-4-yl)-c...)
Affinity DataIC50:  710nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50132364(2-Morpholin-4-yl-6-phenyl-thiopyran-4-one | 2-morp...)
Affinity DataIC50:  720nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178031(7-(2-chlorobenzyloxy)-2-(morpholin-4-yl)-chromen-4...)
Affinity DataIC50:  790nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156497(8-(5-Acetyl-thiophen-2-yl)-2-morpholin-4-yl-chrome...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156499(8-Benzo[b]thiophen-2-yl-2-morpholin-4-yl-chromen-4...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178043(7-(3-methylbenzyloxy)-2-morpholin-4-yl-chromen-4-o...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156499(8-Benzo[b]thiophen-2-yl-2-morpholin-4-yl-chromen-4...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156497(8-(5-Acetyl-thiophen-2-yl)-2-morpholin-4-yl-chrome...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178066(CHEMBL372627 | methyl 3-(2-(morpholin-4-yl)-4-oxo-...)
Affinity DataIC50:  840nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156501(8-(4-Methoxy-phenyl)-2-morpholin-4-yl-chromen-4-on...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156501(8-(4-Methoxy-phenyl)-2-morpholin-4-yl-chromen-4-on...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178070(7-cyclohexylmethoxy-2-(morpholin-4-yl)-chromen-4-o...)
Affinity DataIC50:  940nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50159634(7-Methoxy-2-morpholin-4-yl-chromen-4-one | CHEMBL1...)
Affinity DataIC50:  950nMAssay Description:Inhibition of DNA dependent protein kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50178093(8-(4-acetylphenyl)-2-morpholin-4-ylchromen-4-one |...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School Of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50132359(2-Morpholin-4-yl-6-phenyl-pyran-4-one | 2-morpholi...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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