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Found 420 with Last Name = 'lecci' and Initial = 'c'
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM449872(US10703741, Compound I-15)
Affinity DataIC50:  550nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Mus musculus)
Padlock Therapeutics

US Patent
LigandPNGBDBM449871(US10703741, Compound I-14)
Affinity DataIC50:  550nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Mus musculus)
Padlock Therapeutics

US Patent
LigandPNGBDBM449861(US10703741, Compound I-4 | US10703741, Compound I-...)
Affinity DataIC50:  550nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Mus musculus)
Padlock Therapeutics

US Patent
LigandPNGBDBM449862(US10703741, Compound I-5)
Affinity DataIC50:  550nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Mus musculus)
Padlock Therapeutics

US Patent
LigandPNGBDBM449859(US10703741, Compound I-2)
Affinity DataIC50:  550nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM449859(US10703741, Compound I-2)
Affinity DataIC50:  550nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528737(US11198681, Compound I-62)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528739(US11198681, Compound I-64)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528740(US11198681, Compound I-65)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528740(US11198681, Compound I-65)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528744(US11198681, Compound I-69)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528744(US11198681, Compound I-69)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528746(US11198681, Compound I-70)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528746(US11198681, Compound I-70)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528747(US11198681, Compound I-71)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528749(US11198681, Compound I-73)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528754(US11198681, Compound I-78)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528757(US11198681, Compound I-81)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528758(US11198681, Compound I-82)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528760(US11198681, Compound I-84)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528761(US11198681, Compound I-85)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528762(US11198681, Compound I-86)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528764(US11198681, Compound I-87)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528766(US11198681, Compound I-89)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528769(US11198681, Compound I-92)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528778(US11198681, Compound I-102)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528781(US11198681, Compound I-105)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Mus musculus)
Padlock Therapeutics

US Patent
LigandPNGBDBM528721(US11198681, Compound I-48)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528791(US11198681, Compound I-117)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528790(US11198681, Compound I-115)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528787(US11198681, Compound I-112)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528719(US11198681, Compound I-46)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528784(US11198681, Compound I-108)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528786(US11198681, Compound I-111)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528719(US11198681, Compound I-46)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Mus musculus)
Padlock Therapeutics

US Patent
LigandPNGBDBM528716(US11198681, Compound I-43)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528716(US11198681, Compound I-43)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528710(US11198681, Compound I-37)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528703(US11198681, Compound I-30)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528701(US11198681, Compound I-28)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528693(US11198681, Compound I-20)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528682(US11198681, Compound I-9)
Affinity DataIC50: <1.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM501468(US11026937, Compound I-61)
Affinity DataIC50:  1.50E+3nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM501409(US11026937, Compound I-4)
Affinity DataIC50:  1.50E+3nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM501476(US11026937, Compound I-68)
Affinity DataIC50:  1.50E+3nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM501484(US11026937, Compound I-76)
Affinity DataIC50:  1.50E+3nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM501488(US11026937, Compound I-80)
Affinity DataIC50:  1.50E+3nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM501531(US11026937, Compound I-107)
Affinity DataIC50:  1.50E+3nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM501466(US11026937, Compound I-60)
Affinity DataIC50:  1.50E+3nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM501459(US11026937, Compound I-53)
Affinity DataIC50:  1.50E+3nMAssay Description:Assay buffer (as aforementioned): 100 mM Tris-HCl (pH 7.6), 2 mM DTT, 1 mM CaCl2Final concentrations:100 nM hPAD4 enzyme50 μM (8-fold sub-Km) su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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