Affinity DataKi: 0.00800nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0270nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0440nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0900nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
Affinity DataKi: <0.100nMAssay Description:Inhibition of F-Bak binding to GST-tagged BCL-XL (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.100nMAssay Description:Inhibition of F-Bak binding to GST-tagged BCL2 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibition of F-Bak binding to GST-tagged BCL-XL (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibition of BCL-2 (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.296nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.329nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -53.6kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Inhibition of F-Bak binding to GST-tagged BCL-XL (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataKi: 0.480nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of human CDC7/DBF4 expressed using baculovirus expression system assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by ...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -52.6kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair