Affinity DataKi: 0.220nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by electrochemiluminescent assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.940nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:CDK4/Cyclin D1 and CDK6/Cylcin D3: The Chelation-Enhanced Fluorescence (CHEF) monitors the phosphorylation state in real time where the level of fluo...More data for this Ligand-Target Pair