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Found 510 with Last Name = 'liauw' and Initial = 'ay'
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50097626(1-(3-Carbamimidoyl-phenyl)-1H-tetrazole-5-carboxyl...)
Affinity DataKi:  0.0370nMAssay Description:Inhibition of human purified factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50369433(CHEMBL1202108)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to purified human coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0450nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50369433(CHEMBL1202108)
Affinity DataKi:  0.0450nMAssay Description:The binding affinity towards thrombin obtained from human purified enzymes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079240(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079240(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.110nMAssay Description:Inhibitory activity against factor Xa using human purified enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079240(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.110nMAssay Description:Inhibitory activity against Rabbit factor Xa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289586(3-Methyl-2'-sulfamoyl-biphenyl-4-carboxylic acid [...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079257(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079240(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.170nMAssay Description:Inhibitory activity against trypsin using human purified enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079240(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.170nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50084682(1-[3-(4-Carbamimidoyl-phenyl)-2-(2-methyl-1,2,3,4-...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069172(Boronate Ester analogue | CHEMBL423259)
Affinity DataKi:  0.300nMAssay Description:Inhibition against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079253(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50123033(1-(3-Amino-benzo[d]isoxazol-5-yl)-1H-tetrazole-5-c...)
Affinity DataKi:  0.350nMAssay Description:Inhibition of human purified factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289591(2'-Diethylsulfamoyl-3-methyl-biphenyl-4-carboxylic...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50123037(1-(3-Amino-benzo[d]isoxazol-5-yl)-1H-tetrazole-5-c...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of human purified factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289587(3-Methyl-biphenyl-4-carboxylic acid [(R)-4-guanidi...)
Affinity DataKi:  0.420nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079238(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.440nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289575(3-Methyl-2'-trifluoromethyl-biphenyl-4-carboxylic ...)
Affinity DataKi:  0.460nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079236(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.520nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289591(2'-Diethylsulfamoyl-3-methyl-biphenyl-4-carboxylic...)
Affinity DataKi:  0.620nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289582(3-Methyl-2'-methylsulfonylcarbamate-biphenyl-4-car...)
Affinity DataKi:  0.640nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50084682(1-[3-(4-Carbamimidoyl-phenyl)-2-(2-methyl-1,2,3,4-...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079230(3-(3-Carbamimidoyl-phenyl)-5-ethoxymethyl-4,5-dihy...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079211(CHEMBL327404 | {3-(3-Carbamimidoyl-phenyl)-5-[5-(2...)
Affinity DataKi:  0.830nMAssay Description:Binding affinity to purified human coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079211(CHEMBL327404 | {3-(3-Carbamimidoyl-phenyl)-5-[5-(2...)
Affinity DataKi:  0.830nMAssay Description:Binding affinity to purified human coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079251(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  0.920nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289586(3-Methyl-2'-sulfamoyl-biphenyl-4-carboxylic acid [...)
Affinity DataKi:  0.920nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289576(Biphenyl-4-carboxylic acid [(R)-4-guanidino-1-((2S...)
Affinity DataKi:  0.940nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50123038(1-(3-Amino-benzo[d]isoxazol-5-yl)-1H-tetrazole-5-c...)
Affinity DataKi:  0.980nMAssay Description:Inhibition of human purified factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079250(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  1nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289582(3-Methyl-2'-methylsulfonylcarbamate-biphenyl-4-car...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289598(3-Fluoro-biphenyl-4-carboxylic acid [(R)-4-guanidi...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125240(3-(3-Amino-4-chloro-phenyl)-5-[(thiophene-3-sulfon...)
Affinity DataKi:  1.20nMAssay Description:Inhibitory activity against factor Xa using human purified enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50123035(1-(3-Amino-4-chloro-phenyl)-1H-tetrazole-5-carboxy...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human purified factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079253(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289588(3-Amino-biphenyl-4-carboxylic acid [(R)-4-guanidin...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity against thrombin using human purified enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079236(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-1-ylmethyl-4...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079235(3-(3-Carbamimidoyl-phenyl)-5-tetrazol-2-ylmethyl-4...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069174(Boronate Ester analogue | CHEMBL317682 | N-[(5-Ami...)
Affinity DataKi:  1.70nMAssay Description:Inhibition against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125245(3-(3-Amino-4-chloro-phenyl)-5-(benzenesulfonylamin...)
Affinity DataKi:  1.70nMAssay Description:Inhibitory activity against factor Xa using human purified enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289596(CHEMBL264370 | N-[(1S)-4-{[(Z)-amino(imino)methyl]...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079232(3-(3-Carbamimidoyl-phenyl)-5-ethanesulfonylmethyl-...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50079246(3-(3-Carbamimidoyl-phenyl)-5-[1,2,4]triazol-1-ylme...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity towards human purified Coagulation factor Xa (FXa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069173(CHEMBL2373403 | N-[(R)-5-Amino-1-((1S,2S,6R,8S)-2,...)
Affinity DataKi:  1.80nMAssay Description:Inhibition against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125242(3-(3-Amino-4-chloro-phenyl)-5-(methanesulfonylamin...)
Affinity DataKi:  1.90nMAssay Description:Inhibitory activity against thrombin using human purified enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50069151(CHEMBL2373397 | N-[(R)-5-Amino-1-((1S,2S,6R,8S)-2,...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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