Affinity DataKi: 0.0530nMAssay Description:Displacement of [3H]PF-06883365 from FAP-tagged human GLP-1R expressed in CHO cells assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0920nMAssay Description:Displacement of [125I]GLP-1 from FAP-tagged human GLP-1R expressed in CHO cells assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Displacement of [125I]-17 from human GLP-1R expressed in CHO cell membranes incubated for 120 mins by scintillation counting based radioligand bindin...More data for this Ligand-Target Pair
Affinity DataKi: 0.660nMAssay Description:Displacement of [125I]-17 from human GLP-1R expressed in CHO cell membranes incubated for 120 mins by scintillation counting based radioligand bindin...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of Escherichia coli LpxCMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [125I]GLP-1 from FAP-tagged human GLP-1R expressed in CHO cells assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.01nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [125I]-17 from human GLP-1R expressed in CHO cell membranes incubated for 120 mins by scintillation counting based radioligand bindin...More data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]PF-06883365 from FAP-tagged human GLP-1R expressed in CHO cells assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Binding affinity to CXCR7 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: <13nMAssay Description:Inhibition of human ERG by membrane-competitive-binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [125I]-17 from human GLP-1R expressed in CHO cell membranes incubated for 120 mins by scintillation counting based radioligand bindin...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity to CXCR7 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I]CXCL12 from mouse CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of Escherichia coli LpxCMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Modulation of ProLink-fused human CXCR7 expressed in CHOK1 cell membranes assessed as induction of EA-tagged beta-arrestin recruitment after 30 mins ...More data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 expressed in CHOK1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [125I]CXCL12 from human CXCR7 expressed in CHO-K1 cell membranes after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity to CXCR7 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair